Efficacy and safety of Tinospora cordifolia (Tc) as an add-on therapy in patients with type-2 diabetes

Authors

  • Saumya Mishra Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Narsingh Verma Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Sandeep Bhattacharya Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Kauser Usman Department of Medicine, King George’s Medical University, Lucknow, Uttar Pradesh
  • Himanshu Reddy Department of Medicine, King George’s Medical University, Lucknow, Uttar Pradesh
  • Neera Verma Department of Medicine, King George’s Medical University, Lucknow, Uttar Pradesh
  • Baby Anjum Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Prerna Singh Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Shipra Bharadwaj Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh
  • Kshitij Bharadwaj Department of Physiology, King George’s Medical University, Lucknow, Uttar Pradesh

Keywords:

Type 2 diabetes, Tinospora cordifolia, Oral hypoglycaemic agents

Abstract

Background: Type 2 diabetes has become a global epidemic. Tinospora cordifolia is being used in the treatment of type 2 diabetes since ancient times. It is a common misconception that Ayurvedic medicines are always safe. In fact, they also pose serious health risks either in the form of adverse reactions or in the form of drug interactions. Hence this study was undertaken to study the efficacy and safety of Tc on human subjects.

Methods: We recruited 40 type 2 diabetic patients who were on oral hypoglycaemic agents. These patients were then randomly divided into two groups, A and B. Patients in group A continued with their anti-diabetic medications while in group B Tc was given at a dose of 500 mg three times daily along with their conventional medications. The fasting and post prandial blood glucose levels, renal function tests and liver function tests were recorded at baseline, 3 months and 6 months.

Results: During the course of study we observed a decrease in the fasting and post prandial blood glucose levels of the patients. No significant change was observed in the renal function tests and liver function tests and no other event of any adverse drug reactions were recorded.

Conclusion: Tinospora cordifolia (Tc) is effective as an add-on therapy in patients with type-2 diabetes. There is no negative impact of Tc on the renal as well as liver function tests.

 

References

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Published

2017-01-08

How to Cite

Mishra, S., Verma, N., Bhattacharya, S., Usman, K., Reddy, H., Verma, N., Anjum, B., Singh, P., Bharadwaj, S., & Bharadwaj, K. (2017). Efficacy and safety of Tinospora cordifolia (Tc) as an add-on therapy in patients with type-2 diabetes. International Journal of Research in Medical Sciences, 3(5), 1109–1113. Retrieved from https://www.msjonline.org/index.php/ijrms/article/view/1452

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Original Research Articles