Pancreatoblastoma with multiple peritoneal metastases: a rare entity with atypical presentation and review of literature

Authors

  • Vijay Kumar Verma Department of Radiodiagnosis, Gandhi Medical College, Bhopal, Madhya Pradesh
  • Keerthi Kocherla Department of Radiodiagnosis, Gandhi Medical College, Bhopal, Madhya Pradesh

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150178

Keywords:

Pancreatoblastoma, Hepatoblastoma, Alpha fetoprotein, Ultrasonography, Computed tomography

Abstract

Pancreatoblastoma is a rare primary pancreatic neoplasm that predominantly effects young children and characterized by unique clinical features. Its biological behavior is aggressive with frequent local invasion and metastases. Only hundred cases have been reported in medical literature and its radiological features have been infrequently studied. We report the sonographic, contrast enhanced computed tomography findings of pancreatoblastoma in a 3 year old boy.

References

Becker WF. Pancreatoduodenectomy for carcinoma of the pancreas of infant: report of a case. Ann Surg. 1957;145:864-70.

Horie A, Yano Y, Kotoo Y, Miwa A. Morphogenesis of pancreatoblastoma, infantile carcinoma of the pancreas: report of two cases. Cancer. 1977;39:247-54.

Montemarano H, Lonergan G, Bulas D, Selby D. Pancreatoblastoma: imaging findings in 10 patients and review of the literature. Radiology. 2000;214:476-82.

Klimsra DS, Wenig BM, Adair CF, Hefess CS. Pancreatoblastoma: a clinicopathologic study and review of literature. Am J Surg Pathol. 1995;12:1371-89.

Chung EM, Travis MD, Conran RM. Pancreatic tumors in children: radiologic-pathologic correlation. Radiographics. 2006;26:1211-38.

Kloppel G, Maillet B. Classification and staging of pancreatic nonendocrine tumors. Radiol Clin North Am. 1989;27:105-19.

Saif MW. Pancreatoblastoma. JOP J Pancreas. 2007;8:55-63.

Shorter N, Glick R, Klimstra D, Brennan MF, Laquaglia MP. Malignant pancreatic tumors in childhood and adolescence: the Memorial Sloan-Kettering experience, 1967 to present. J Pediatr Surg. 2002;37:887-92.

Defachelles AS, Martin De Lassalle E, Boutard P, Nelken B, Schneider P, Patte C. Pancreatoblastoma in childhood: clinical course and therapeutic management of seven patients. Med Pediatr Oncol. 2001;37:47-52.

Du E, Katz M, Weidner N, Yoder S, Moosa AR, Shabaik A. Ampullary Pancreatoblastoma in an elderly patient: a case report and review of the literature. Arch Pathol Lab Med. 2003;127:1501-5.

Cohen MD. Imaging of children with cancer. In: Cohen MD, eds. A Book. 3rd ed. St. Louis, Mo: Mosby-Year Book; 1992; 20-24, 52-62, 89-106, 134-156.

Gupta AK, Mitra DK, Berry M, Dinda AK, Bhatnagar V. Sonography and CT of pancreatoblastoma in children. AJR Am J Roentgenol. 2000;174(6):1639-41.

Passmore SJ, Berry PJ, Oakhill A. Recurrent pancreatoblastoma with inappropriate adrenocorticotropic hormone secretion. Arch Dis Child. 1988;63:1494-6.

Roebuck DJ, Yuen MK, Wong YC, Shing MK, Lee CW, Li CK. Imaging features of pancreatoblastoma. Pediatr Radiol. 2001;31(7):501-6.

Lee JY, Kim IO, Kim WS, Kim CW, Yeon KM. CT and US findings of pancreatoblastoma. J Comput Assist Tomogr. 1996;20:370-4.

Immanura A, Nakagawa A, Okuno M, Takai S, Komada H, Kwon AH, et al. Pabcreatoblastoma in an adolescent girl:case report and review of 26 Japanese cases. Eur J Surg. 1998;164(4):309-12.

Stephenson CA, Kletzel M, Seibert JJ, Glasier CM. Pancreatoblastoma: MR appearance. J Comput Assist Tomogr. 1990;14:492-3.

Mergo PJ, Helmberger TK, Buetow PC, Helmberger RC, Ros PR. Pancreatic neoplasms: MR imaging and pathologic correlation. Radiographics. 1997;17:281-301.

Lumkin B, Anderson MW, Ablin DS, McGahan JP. CT, MRI and color Doppler correlation of pancreatoblastoma: a case report. Pediatr Radiol. 1993;23:61-2.

Downloads

Published

2017-01-09

How to Cite

Verma, V. K., & Kocherla, K. (2017). Pancreatoblastoma with multiple peritoneal metastases: a rare entity with atypical presentation and review of literature. International Journal of Research in Medical Sciences, 3(6), 1514–1517. https://doi.org/10.18203/2320-6012.ijrms20150178

Issue

Section

Case Reports