A case of rheumatoid arthritis with features of systemic lupus erythematosus

Authors

  • Deepak Kumar Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand
  • Abhinaba Debnath Department of Medicine, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand

DOI:

https://doi.org/10.18203/2320-6012.ijrms20161268

Keywords:

SLE, RA, Rhupus

Abstract

A 50 year old female presented with features qualifying for both rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Patient fulfilled 10/10 ACR-EULAR criteria for RA, her anti-CCP was positive (21.6 RU/ml), her DAS28 score was 7.55 (favouring RA) and she fulfilled ≥4  of  11 criteria’s of SLE  (definite SLE). Coexistence of SLE and RA is known as “rhupus”. The immunopathological process of SLE and RA are considered to be exact opposite of one another so their coexistence remains one of the debated topics of rheumatology.

References

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Panush RS, Edwards NL, Longley S, Webster E. 'Rhupus syndrome'. Arch Intern Med. 1988;148:1633-6.

Simon JA, Granados J, Cabiedes J, Morales JR, Varela JA. Clinical and immunogenetic characterization of Mexican patients with 'rhupus'. Lupus. 2002;11:287-92.

Amezcua-Guerra LM, Springall R, Marquez-Velasco R, Gómez-García L, Vargas A, Bojalil R. Presence of antibodies against cyclic citrullinated peptides in patients with “rhupus”: a cross-sectional study. Arthritis Res Ther. 2006;8(5):R144.

Cohen MG, Webb J. Concurrence of rhumatoïde arthritis and systemic lupus erythematosus:report of 11 cases. Ann Rheum Dis. 1987;46:853-8.

Damian-Abrego GN, Cabiedes J, Cabral AR. Anti-citrullinated peptide antibodies in lupus patients with or without deforming arthropathy. Lupus. 2008;17:300-4.

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Published

2016-12-30

How to Cite

Kumar, D., & Debnath, A. (2016). A case of rheumatoid arthritis with features of systemic lupus erythematosus. International Journal of Research in Medical Sciences, 4(5), 1765–1767. https://doi.org/10.18203/2320-6012.ijrms20161268

Issue

Section

Case Reports