Hearing loss and vertigo among COVID-19 patients: a review

Authors

  • Santosh Kumar Swain Department of Otorhinolaryngology and Head and Neck Surgery, IMS and SUM Hospital, Siksha “O” Anusandhan University, Kalinga Nagar, Bhubaneswar, Odisha, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20213434

Keywords:

COVID-19, SARS-CoV-2, Vestibulocochlear manifestations, Sensorineural hearing loss, Vertigo

Abstract

The coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The clinical presentations of the COVID-9 patients vary from mild respiratory illness to fatal possible outcomes like death. SARS-CoV-2 infection can cause a wide range of extrapulmonary manifestations including sensory and neural complications like olfactory and/or gustatory dysfunction,otologic manifestations and long-term neurological complications. The association between the COVID-19 infection and hearing loss and vertigo make intuitive sense, give neuropathic manifestations of the inner ear resulting in cochleovestibular symptoms. Hearing loss and vertigo are interesting clinical outcomes associated with COVID-19 infections. Hearing loss and vertigo in COVID-19 patients have not received much attention from medical professionals. COVID-19 infection could have deleterious effects on the inner ear despite patients are asymptomatic. Hearing loss and vertigo play an important role for affecting routine activity and result in invisible handicap of the affected person and psychological solitary confinement. In current COVID-19 pandemic, some patients of COVID-19 are presenting with cochleovestibular symptoms such as hearing loss, vertigo and tinnitus. The proper understanding of the pathophysiology behind the hearing loss and vertigo in COVID-19 infections requires further research.This review article discusses the details of this epidemiology, etiopathology, assessment and management of the hearing loss and vertigo among COVID-19 patients.

References

Swain SK, Acharya S, Sahajan N. Otorhinolaryngological manifestations in COVID-19 infections: An early indicator for isolating the positive cases. J Sci Soc. 2020;47(2):63-8.

Swain SK, Jena PP, Das S, Gupta A. COVID-19 Associated Mucormycosis in Head and Neck Region: Our Experiences at a Tertiary Care Teaching Hospital of Eastern India. Siriraj Med J. 2021;73(7):423-8.

Lechien JR, Chiesa-Estomba CM, De Siati DR, Horoi M, Le Bon SD, Rodriguez A, et al. Olfactory and gustatory dysfunctions as a clinical presentation of mild-to-moderate forms of the coronavirus disease (COVID-19): a multicenter European study. Eur Arch Oto-Rhino-Laryngol. 2020;277(8):2251-61.

Goddard JC, Fayad JN. Vestibular neuritis. Otolaryngol Clin N Am. 2011;44:361-5.

Swain SK, Jena PP. Clinical implications and future perspective of COVID-19 pandemic-a review. Int J Adv Med. 2021;8(2):334-40.

Swain SK, Agrawal R. Mastoid surgery: a high-risk aerosol generating surgical procedure in COVID-19 pandemic. Int J Otorhinolaryngol Head Neck Surg. 2020;6(10):1941-6.

Swain SK, Pani SR. Incidence of Hearing Loss in COVID-19 Patients: A COVID Hospital-based Study in the Eastern Part of India. Int J Curr Res Rev. 2020; 13:103-7.

Wege H, Watanabe R, ter Meulen V. Relapsing subacute demyelinating encephalomyelitis in rats during the course of coronavirus JHM infection. J Neuroimmunol. 1984;6(5):325-36.

Kilic O, Kalcioglu MT, Cag Y, Tuysuz O, Pektas E, Caskurlu H, et al. Could sudden sensorineural hearing loss be the sole manifestation of COVID-19? An investigation into SARS-COV-2 in the etiology of sudden sensorineural hearing loss. Int J Infect Dis. 2020;97:208-11.

Almufarrij I., Munro K.J. One year on: An updated systematic review of SARS-CoV-2, COVID-19 and audio-vestibular symptoms. Int J Audiol. 2021:1-11.

Swain SK, Choudhury J, Acharya S. Herpes zoster oticus among pediatric patients: Our experiences at a tertiary care teaching hospital. Indian J Health Sci Biomed Res. 2020;13(3):215-20.

Mateer EJ, Huang C, Shehu NY, Paessler S. Lassa fever-induced sensorineural hearing loss: neglected public health and social burden. PLoS Negl Trop Dis. 2018;12:e0006187.

Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683-90.

Goddard JC, Fayad JN. Vestibular neuritis. Otolaryngol Clin N Am. 2011;44:361-5.

Mustafa MWM. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41:102483.

Wilson WR. The relationship of the herpes virus family to sudden hearing loss: a prospective clinical study and literature review. Laryngoscope. 1989;96: 870-7.

Cashman KA, Wilkinson ER, Zeng X, Cardile AP, Facemire PR, Bell TM, et al. Immune-mediated systemic vasculitis as the proposed cause of sudden-onset sensorineural hearing loss following lassa virus exposure in cynomolgus macaques. MBio. 2018; 9:1896-918.

Mateer EJ, Huang C, Shehu NY, Paessler S. Lassa fever-induced sensorineural hearing loss: a neglected public health and social burden. PLoS Negl Trop Dis. 2018;12:e0006187.

Cohen BE, Durstenfeld A, Roehm PC. Viral causes of hearing loss: a review for hearing health professionals. Trends Hearing. 2014;18:1-17.

Swain SK, Kumar S. Infection control measures during COVID-19 pandemic–An otorhinolaryngological and head-and-neck perspective. Indian J Health Sci Biomed Res. 2021; 14(1):3-11.

Guo YR, Cao QD, Hong ZS, Tan YY, Chen SD, Jin HJ, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak–an update on the status. Military Med Res. 2020;7(1):1-10.

Solomon IH, Normandin E, Bhattacharyya S, Mukerji SS, Keller K, Ali AS, et al. Neuropathological features of Covid-19. New Eng J Med. 2020; 383(10):989-92.

Krajewska J, Krajewski W, Zub K, Zatoński T. COVID-19 in otolaryngologist practice: a review of current knowledge. Eur Arch Oto-Rhino-Laryngol. 2020;277(7):1885-97.

Swain SK. Sudden onset of olfactory and gustatory dysfunction-An early predictor to isolate the patient in COVID-19 pandemic. Indian J Health Sci Biomed Res. 2021;14(2):173-7.

Swain SK, Janardan S, Mohanty JN. Endoscopy guided eustachian tube balloon dilation: Our experiences. Iranian J Otorhinolaryngol. 2020; 32(112):287-94.

Cui C, Yao Q, Di Zhang YZ, Zhang K, Nisenbaum E, Cao P, et al. Approaching otolaryngology patients during the COVID-19 pandemic. Otolaryngol Head Neck Surg. 2020;1(2):234-7.

Mustafa MWM. Audiological profile of asymptomatic Covid-19 PCR-positive cases. Am J Otolaryngol. 2020;41:102483.

Bai WZ, Hashikawa T. The neuroinvasive potential of SARSCoV2 may be at least partially responsible for the respiratory failure of COVID-19 patients. J Med Virol. 2020;92:552-5.

Mao L, Jin H, Wang M, Hu Y, Chen S, He Q, et al. Neurologic manifestations of hospitalized patients with coronavirus disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683-90.

Swain SK, Das S, Lenka S. Sudden Sensorineural Hearing Loss among COVID-19 Patients-Our Experiences at an Indian Teaching Hospital. Siriraj Med J. 2021;73(2):77-83.

Ashrafi MR, Azizimalamiri R, Badv RS, Tavasoli AR, Nikkhah A, Montazerlotfelahi H, et al. Coronavirus, its neurologic manifestations, and complications. Iranian J Pediatr. 2020;30(2):1-4.

Venhovens J, Meulstee J, Verhagen WIM. Acute vestibular syndrome: a critical review and diagnostic algorithm concerning the clinical differentiation of peripheral versus central aetiologies in the emergency department. J Neurol. 2016;263:2151-7.

Swain SK. Age related hearing loss and cognitive impairment-a current perspective Int J Res Med Sci. 2021;9(1):317-21.

Viljanen A, Kaprio J, Pyykkö I, Sorri M, Pajala S, Kauppinen M, et al. Hearing as a predictor of falls and postural balance in older female twins. J Gerontol Series. 2009;64(2):312-7.

Gluth MB, Nelson EG. Age-Related change in vestibular ganglion cell populations in individuals with presbycusis and normal hearing. Otol Neurotol. 2017;38:540-6.

Niazkar HR, Zibaee B, Nasimi A, Bahri N. The neurological manifestations of COVID-19: a review article. Neurol Sci. 2020;41:1667-71.

Zhao W, Zhong Z, Xie X, Yu Q, Liu J.Relation between chest CT findings and clinical conditions of Coronavirus disease (COVID-19) pneumonia: a multicenter study. Am J Roentgenol. 2020;214(5): 1072-7.

Ramasamy K. The War of United States of America with COVID-19. Int J Cur Res Rev. 2020;12(16):18-28.

Lee H, Sohn SI, Cho YW, Lee SR, Ahn BH, Park BR, et al. Cerebellar infarction presenting isolated vertigo. Frequency and vascular topographical patterns. Neurology. 2006;67:1178-83.

Swain S, Behera IC, Sahu MC. Prevalence of Benign Paroxysmal Positional Vertigo: Our experiences at a tertiary care hospital of India. Egyptian J Ear, Nose, Throat and Allied Sci. 2018;19(3):87-92.

Swain SK, Sahu MC, Choudhury J. Sudden sensorineural hearing loss in children: Our experiences in tertiary care teaching hospital of eastern India. Pediatria Polska-Polish J Paediatr. 2018;93(2):127-31.

Swain SK, Das A, Sahu MC, Das R. Neonatal hearing screening: Our experiences at a tertiary care teaching hospital of eastern India. Pediatria Polska. 2017; 92(6):711-5.

Wang M, Cao R, Zhang L, Yang X, Liu J, Xu M, et al. Remdesivir andchloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro. Cell Res. 2020;30:269-71.

Swain SK, Pati BK, Mohanty JN. Otological manifestations in pregnant women-A study at a tertiary care hospital of eastern India. J Otol. 2020; 15(3):103-6.

Swain SK, Behera IC. Managing pediatric otorhinolaryngology patients in coronavirus disease-19 pandemic–A real challenge to the clinicians. Indian J Child Health. 2020;7(9):357-62.

Zadeh MH, Storper IS, Spitzer JB. Diagnosis and treatment of suddenonset sensorineural hearing loss: a study of 51 patients. Otolaryngol Head Neck Surg. 2003128:92-8.

Nosrati-Zarenoe R, Hultcrantz E. Corticosteroid treatment of idiopathic sudden sensorineural hearing loss: randomized triple-blind placebo-controlled trial. Otol Neurotol. 2012;33:523-31.

Swain SK, Pani SR. Hearing loss: A neglected and morbid clinical entity in Corona Virus Disease 2019 pandemic. Amrita J Med. 2020;16(4):159-63.

Malayala SV, Raza A. A case of COVID-19-induced vestibular neuritis. Cureus. 2020;12(6):8918.

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Published

2021-08-25

How to Cite

Swain, S. K. (2021). Hearing loss and vertigo among COVID-19 patients: a review. International Journal of Research in Medical Sciences, 9(9), 2863–2868. https://doi.org/10.18203/2320-6012.ijrms20213434

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Section

Review Articles