Morbidity, mortality and clinico-laboratory profile of COVID-19 related illness in children: a retrospective observational study from a tertiary care centre in India

Authors

  • Bijoy Patra Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India http://orcid.org/0000-0001-5162-7127
  • Manju Nimesh Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India
  • Parasdeep Kaur Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India
  • Sumantha Patil Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India
  • Hema Gupta Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India
  • Saria Jilowa Department of Radiology, ABVIMS and Dr. RML Hospital, Delhi, India
  • Dheeraj Bahl Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20215044

Keywords:

Morbidity, Mortality, Clinico-laboratory profile, COVID-19, MISC

Abstract

Background: As India is poised for a third wave of SARS Co-V2 infection with a large unvaccinated pediatric population, it becomes imperative and pertinent for a study to find out its demographic, clinico-laboratory profile, and outcome in children with COVID-19 disease and its related illness.

Methods: This is a retrospective observational study undertaken for Children and Adolescent admitted in the department of pediatrics of a teaching and tertiary care referral hospital, Delhi.

Results: The median age of admitted children with COVID-19 disease was 11 years with an interquartile range 3 to 16 years. The median duration of hospital stay was 10 days (mean: 18±14 days). Mortality was 9/62 (14%). Recovery in non-severe (asymptomatic, mild, moderate) was 41/41 (100%), and in severe and critical illness including MISC was 42.8% (9/21). Mortality in severe and critical patients managed in SARI and COVID ward was 44% (8/18). Death among MISC patient in PICU was 33% (1/3). Difference in CRP rise was significant in severe and non-severe group of COVID-19 (p=0.017).

Conclusions: Even though the morbidity and mortality associated with COVID-19 infection and related illness seems to be miniscule, the infection causes significant illness in the subgroup of children who requires hospitalization and can be fatal in those with comorbidity.

Author Biographies

Bijoy Patra, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

Consultant  & HOU(P 2 unit and PICU)

Department of Pediatrics

ABVIMS & Dr RML Hospital,Delhi.

Manju Nimesh, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

Senior Specialist

Department of Pediatrics

ABVIMS & Dr. RML Hospital

Delhi.

Parasdeep Kaur, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

Senior Resident

Department of Pediatrics

ABVIMS & Dr. RML Hospital,Delhi.

Sumantha Patil, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

Post graduate student

Department of Pediatrics

ABVIMS & Dr. RML Hospital,Delhi.

Hema Gupta, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

Associate Professor

Department of Pediatrics

ABVIMS & Dr. RML Hospital

Delhi

Saria Jilowa, Department of Radiology, ABVIMS and Dr. RML Hospital, Delhi, India

Professor

Departmen of radiodiagnosis

ABVIMS & Dr. RML Hospital

Delhi

Dheeraj Bahl, Department of Pediatrics, ABVIMS and Dr. RML Hospital, Delhi, India

HOD(Pediatrics) & Additional Medical Superientendent

ABVIMS & Dr. RML Hospital,Delhi.

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Published

2021-12-28

How to Cite

Patra, B., Nimesh, M., Kaur, P., Patil, S., Gupta, H., Jilowa, S., & Bahl, D. (2021). Morbidity, mortality and clinico-laboratory profile of COVID-19 related illness in children: a retrospective observational study from a tertiary care centre in India. International Journal of Research in Medical Sciences, 10(1), 133–140. https://doi.org/10.18203/2320-6012.ijrms20215044

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Section

Original Research Articles