Role of Topical Corticosteroid Therapy in Various Dermatoses

Authors

  • Jitendra Kishore Singh Department of Dermatology, Juran Chhapra, Muzzafarpur, Bihar, India
  • Yogesh Rupram Zanwar Department of Dermatology, Skin and Hair Clinic, Badnera Road, Amravati, Maharashtra, India
  • Jagannath Kumar Department of Dermatology, SS Institute of Medical Sciences & Research Center, Davengere, Karnataka, India
  • Jatin Jayeshbhai Patel Department of Dermatology, Orchid Hospital, Rajkot, Gujarat, India
  • Vineet Chandrabhushan Dube Department of Dermatology, Vinit Dube Skin Care Clinic, Chandrapur, Maharashtra, India
  • Madhurendra Kumar Sinha Department of Dermatology, Sinha Skin Hospital, Patna, Bihar, India
  • Tanushree Biswas Department of Dermatology, Apollo Clinic, Bangalore, Karnataka, India
  • Ramchander Dharak Department of Dermatology, Karuna Sree Hospital, Warangal, Telangana, India
  • Pankaj Tiwary Department of Dermatology, Skin clinic, Lalbagh, Patna, Bihar, India
  • Priyanka Kartik Sutariya Department of Dermatology, Skin Experts Advanced Skin, Laser & Cosmetology Clinic, Rajkot, Gujarat, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20214048

Keywords:

Plaque psoriasis, CP 0.025%, Topical corticosteroid

Abstract

Topical corticosteroids are the cornerstone in managing several dermatologic disorders, including plaque psoriasis.Managing plaque psoriasis warrants the use of an effective anti-inflammatory, antimitotic, antipruritic, and immunosuppressive agent, such as clobetasol propionate (CP). Recently, CP 0.025% cream received approval by United States food and drug administration (US FDA) for the treatment of moderate-to-severe psoriasis in adult patients. CP 0.025% cream has proven efficacious in chronic skin diseases, including controlling inflammation and pruritus, in various steroid-responsive dermatoses. In contrast to prior CP formulations, this novel CP 0.025% cream formulation does not contain propylene glycol, short-chain alcohols, and sorbitol-based emulsifiers, which are known contact allergens. The other beneficial attributes of this CP 0.025% cream formulation are high penetration of active ingredients and a lower degree of systemic absorption. This case series discusses the experience of using CP 0.025% cream in terms of its efficacy and safety in various dermatologic conditions. 

References

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Published

2021-10-28

How to Cite

Singh, J. K., Zanwar, Y. R., Kumar, J., Patel, J. J., Dube, V. C., Sinha, M. K., Biswas, T., Dharak, R., Tiwary, P., & Sutariya, P. K. (2021). Role of Topical Corticosteroid Therapy in Various Dermatoses. International Journal of Research in Medical Sciences, 9(11), 3434–3441. https://doi.org/10.18203/2320-6012.ijrms20214048

Issue

Section

Case Series