Burden and quality of life in caregivers of obsessive-compulsive disorder and schizophrenia: a cross-sectional study


  • M. Afzal Institute of Mental health and Hospital, Agra, India
  • Sandhyarani Mohanty Institute of Mental health and Hospital, Agra, India
  • Anil Kumar Sisodia Institute of Mental health and Hospital, Agra, India




Burden of care, Families of psychiatric patients, Schizophrenia, Obsessive-compulsive disorder, Quality of life


Background: Obsessive–compulsive disorder (OCD) and schizophrenia both are chronic and disabling mental illness which imposes considerable burden on caregivers. Many studies have also reported that both of them have a negative impact on the quality of life (QOL) of both the patients and the caregivers living with the patients. The aim of the study was to assess and compare the burden of care and quality of life (QoL) in the care givers of patients with Obsessive–Compulsive Disorder (OCD) and Schizophrenia.

Methods: The present study is a hospital based, cross-sectional and comparative study. 30 patients with schizophrenia and 30 Obsessive-Compulsive Disorder patients and their caregivers attending the OPD and family ward of Institute of Mental Health and Hospital, Agra were selected through purposive sampling with specific inclusion and exclusion criteria. World Health Organization Quality of Life Scale (BREF version), Burden Assessment Schedule, Positive and Negative Syndrome Scale (PANSS), Yale–Brown Obsessive Compulsive Scale (Y-BOCS) were used for assessment.

Results: The findings of this study revealed remarkable burden in the caregivers of OCD and Schizophrenia patients along with considerable and comparable impairment of their quality of life. Caregivers of Schizophrenia patients experienced more burden and have poor quality of life than the caregivers of OCD patients.

Conclusions: It is suggested to develop effective strategies for family intervention with the purpose of supporting the caregivers and improving their quality of life.

Author Biography

M. Afzal, Institute of Mental health and Hospital, Agra, India

Resident, Department of Psychiatry, Institute of Mental Health and Hospital, Agra-282002


Karno M, Golding JM, Sorenson SB, Burnam MA. The epidemiology of obsessive-compulsive disorder in five US communities. Arch Gen Psychiatry. 1988;45:1094-9.

Weissman MM, Bland RC, Canino GJ, Greenwald S, Hwu HG, LeeCK, et al. The cross-national epidemiology of obsessive compulsive disorder. J Clin Psychiatry. 1994;55:5-10.

Steketee G. Disability and family burden in obsessive-compulsive disorder. Can J Psychiatry. 1997;42:919-28.

Bystritsky A, Liberman RP, Hwang S, Wallace CJ, Vapnik T, MaindmentK, et al. Social functioning and quality of life comparisons between obsessive compulsive and schizophrenic disorders. Depress Anxiety. 2001;14:214-8.

Vikas A, Avasthi A, Sharan P. Psychological impact of obsessive compulsive disorder on patients and their caregivers: a comparative study with depressive disorder. Int J Soc Psychiatry. 2009;57:45-56.

Gururaj GP, Math S, Reddy JYC, Chandrashekar CR. Family burden, quality of life and disability in obsessive compulsive disorder: an Indian perspective. J Postgrad Med. 2008;54:91-7.

Stengler-Wenzke K, Kroll M, Matschinger H, Angermeyer MC. Quality of life of relatives of patients with obsessive-compulsive disorder. Compr Psychiatry. 2006;47:523-7.

Albert U, Salvi V, Saracco P, Bogetto F, Maina G. Health‐related quality of life among first‐degree relatives of patients with obsessive‐compulsive disorder in Italy. Psychiatr Serv. 2007;58:970-6.

Garre J, Hernández M, Lozano M, Vilalta J, Turón A, Cruz Ma et al. Carga y calidad de vida en cuidadores de pacientes con demencia tipo Alzheimer. Rev Neurol. 2000;31:522-7.

Aguilar M. Estudios de calidad de vida en el marco urbano de las demencias. Rev Neurol. 1998;28:80-4.

Lochner C, Mogotsi M, du Toit PL, Kaminer D, Niehaus DJ, Stein DJ. Quality of life in anxiety disorders: A comparison of obsessive-compulsive disorder, social anxiety disorder and panic disorder. Psychopathology. 2003;36:255-62.

Shetti CN, Reddy YC, Kandavel T, Kashyap K, Singisetti S, Hiremath AS, et al. Clinical predictors of drug nonresponse in obsessive-compulsive disorder. J Clin Psychiatry. 2005;66:1517-23.

Bobes J, Gonzαlez MP, Bascarαn MT, Arango C, Sαiz PA, Bousoρo M. Quality of life and disability in patients with obsessive-compulsive disorder. Eur Psychiatry. 2001;16:239-45.

Chakrabarti S, Kulhara P, Verma SK. Family burden of neurosis: extent and determinants. Hong Kong J Psychiatry 1996;6:23-8.

Magliano L, Tosini P, Guarneri M, Marasco C, Catapano F. Burden on the families of patients with obsessive‐compulsive disorder: a pilot study. Eur Psychiatry. 1996;11:192-7.

Black DW, Gafney G, Schlosser S, Gabel J. The impact of obsessive‐compulsive disorder on the family: preliminary findings. J Nerv Ment Dise. 1998;186:440-42.

Stengler-Wenzke K, Trosbach J, Dietrich S, Angermeyer MC. Subjective burden and coping strategies of relatives of patients with OCD. J Adv Nurs. 2004;48:35-42.

Renshaw KD, Chambless DL, Rodebaugh TL, Steketee G. Living with severe anxiety disorders: Relatives' distress and reactions to patient behaviours. Clin Psychol Psychother. 2000;7:190-200.

Gutiérrez-Maldonado J, Caqueo-Urízar A, Kavanagh D. Burden of care and general health in families of patients with schizophrenia. Soc Psychiatry Psichiatr Epidemiol. 2005;40:899-904.

Calvocoressi L, Lewis B, Harris M, Trufan SJ, Goodman WK, McDougle CJ, et al. Family accommodation in obsessive-compulsive disorder. Am J Psychiatry. 1995;152:441-3.

Jayakumar C, Jagadheesan K, Verma AN. Caregiver's burden: a comparison between obsessive compulsive disorder and schizophrenia. Indian J Psychiatry. 2002;44:337-42.

Thomas JK. Thomas JK, Suresh Kumar PN, Verma AN, et al. Psychosocial dysfunction and family burden in schizophrenia and obsessive-compulsive disorder. Indian Journal of Psychiatry. 2004;46(3):238-43.

Kalra H, Nischal A, Trivedi JK. Extent and determinants of burden of care in Indian families: A comparison between obsessive-compulsive disorder and schizophrenia. The International Journal of Social Psychiatry. 2009;55(1):28-38.

Barría J. Síndrome de Burnout en Asistentes Sociales del Servicio Nacional de Menores de la Región Metropolitana. Psykhe. 2003;12:213-26.

Quintana C. El Síndrome de Burnout en Operadores y Equipos de Trabajo en Maltrato Infantil Grave. Psykhe. 2005;14:55-68.

WHOQOL Group. The World Health Organization Quality of Life Assessment (the WHOQOL-BREF): position paper from the World Health Organisation. Social Science and Medicine. 1998;41:1403-9.

Thara R, Padmavati R, Kumar S. Burden Assessment Schedule: Instrument to assess burden on caregivers of chronic mentally ill. Indian Journal of Psychiatry. 1998;40:21-9.

Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophrenia Bulletin. 1987;13:261-76.

Goodman W, Price L, Rasmussen S. The Yale-Brown obsessive compulsive scale: validity. Archives of General Psychiatry. 1989;46:1012-16.

Oza H. Oza H, Parikh MN, Vankar GK. Comparison of caregiver burden in schizophrenia and obsessive-compulsive disorder. Archives of Psychiatry and Psychotherapy. 2017;19(2):32-41.

Aswal S, Aswal VK, Verma A. Examining the role of Duration of illness on the level of mental disability in Obsessive Compulsive Disorder. International Journal of Health and Clinical Research. 2020;3(3):72-5.

Kaushal A, Sinha P, Garg A. Caregiver burden and its effect on Quality of Life in caregivers of OCD: A clinic based case-control study from Northern India. Delhi Psychiatry Journal. 2016;19(1):53-64.

Veltro F, Maglian L, Lobrace S. Burden on the relatives of patients with schizophrenia versus neurotic disorders: A pilot study. Social Psychiatry and Psychiatric Epidemiology. 1994;29(2):66-70.

Negm M, Mahdy R, Khashaba AA. Comparison of family burden, quality of life, and disability in obsessive compulsive disorder and schizophrenia in Zagazig University Hospitals. Egyptian Journal of Psychiatry. 2014;35(1):39-44.

Solanki RK, Singh P, Midha A. Disability and quality of life in schizophrenia and obsessive compulsive disorder: a cross-sectional comparative study. East Asian Archives of Psychiatry: official journal of the Hong Kong College of Psychiatrists = Dong Yajingshenkexuezhi: Xianggangjingshenkeyixue yuan qi kan. 2010;20(1):7-13.




How to Cite

Afzal, M., Mohanty, S., & Sisodia, A. K. (2021). Burden and quality of life in caregivers of obsessive-compulsive disorder and schizophrenia: a cross-sectional study. International Journal of Research in Medical Sciences, 10(1), 159–166. https://doi.org/10.18203/2320-6012.ijrms20215048



Original Research Articles