Histomorphological spectrum of central nervous system lesions in a tertiary care hospital

Authors

  • Hetal Kirit Shah Pravara institute of medDepartment of Pathology, Rural Medical College, Pravara Institute of Medical Sciences (DU), Maharashtra, India ical sciences
  • Suryakant Dongre Department of Pathology, Rural Medical College, Pravara Institute of Medical Sciences (DU), Maharashtra, India
  • Ravindra Karle Department of Pathology, Rural Medical College, Pravara Institute of Medical Sciences (DU), Maharashtra, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20215036

Keywords:

CNS lesions, CNS tumors, Histopathological

Abstract

Background: Central nervous system (CNS) lesions show considerable geographic and racial variations with respect to the incidence and their pattern of distribution. CNS neoplasm account for 2% of all cancers. There has been a rapid increase in incidence of CNS tumors. Many non-neoplastic CNS lesions can clinically and radiologically mimic brain tumors and to differentiate them histopathological examination is necessary.

Methods: This was a descriptive cross-sectional study of 30 cases, carried out from March 2020 to February 2021, in a tertiary health care hospital. The cases were diagnosed histopathologically and categorized according to the WHO 2021 classification.

Results: The study included 30 cases. 3 (10%) of them were non-neoplastic while 27 (90%) were neoplastic with glioblastoma and diffuse astrocytoma being the most common. Overall, tumors of neuroepithelial tissue (60%) was the most common entity. Frontal lobe was the most commonly observed site in the neoplastic lesion. Headache was the most common presentation. Age range varied from 7 years to 66 years with the mean age of 32.7 years.

Conclusions: The spectrum of neoplastic lesions were astrocytoma, glioblastoma, ependymoma, hemagioblastoma, medulloblastoma, meningioma, non-hodgkins lymphoma, oligodendroglioma, pitutary adenoma, schwannoma and non-neoplastic were A-V malformation, brain abscess, subdural empyema.

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Published

2021-12-28

How to Cite

Shah, H. K., Dongre, S., & Karle, R. (2021). Histomorphological spectrum of central nervous system lesions in a tertiary care hospital. International Journal of Research in Medical Sciences, 10(1), 86–91. https://doi.org/10.18203/2320-6012.ijrms20215036

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Original Research Articles