Acute myeloid leukemia, secondary to myelodysplastic syndrome, debuting as thrombotic thrombocytopenic purpura: case report

Authors

  • Jose Miguel Huerta Velázquez Department of Hematology, Universidad Autónoma de Guadalajara, Guadalajara, México

DOI:

https://doi.org/10.18203/2320-6012.ijrms20220305

Keywords:

Thrombotic TTP, AML, MDS, Microangiopathic hemolytic anemia, PTT

Abstract

We present a case of myelodysplastic syndrome (MDS) that progressed to acute myeloid leukemia (AML) with changes related to myelodysplasia that presented as thrombotic thrombocytopenic purpura (TTP). After a failure in response to plasmapheresis therapy and a poor long-term prognosis, the family opted for palliative care, the patient dying on the eleventh day of hospitalization. The case is an extremely rare presentation of a rare condition, as it is the second reported case of AML with myelodysplasia-related changes presenting as TTP, and the first reported case of TTP secondary to AML secondary to MDS.

References

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Published

2022-01-29

How to Cite

Huerta Velázquez, J. M. (2022). Acute myeloid leukemia, secondary to myelodysplastic syndrome, debuting as thrombotic thrombocytopenic purpura: case report. International Journal of Research in Medical Sciences, 10(2), 530–532. https://doi.org/10.18203/2320-6012.ijrms20220305

Issue

Section

Case Reports