COVID-19 pneumonia and mucormycosis a new challenging duo- rhino-occulo-cerebral mucormycosis: a case report

Authors

  • Sudhir K. Atri Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India
  • Sanjay Fotedar Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India
  • Homdutt . Department of Medicine, Sanjay Gandhi Memorial Hospital, Magolpuri, Delhi, India
  • Vinay Malik Department of Radiology, Healthmap Diagnostics, Rohtak, Haryana, India
  • Parul Punia Department of Microbiology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20221498

Keywords:

COVID-19, Pneumonia, Mucormycosis, Rhino-oculo-cerebral mucormycosis

Abstract

The pandemic of corona virus disease 2019 (COVID-19) has posed challenge not only in management of the primary disease but the emerging complications associated with COVID-19 has further complicated the course of disease. The course of COVID-19 disease is associated with infectious and noninfectious complications former include secondary bacterial and fungal infection adding to mortality and morbidity. COVID-19 disease associated candidiasis and aspergillosis have been reported as super infections but with the steroid and supplemental oxygen as mainstay treatment modality mucormycosis is now complicating the course of disease and presently posing challenge in India with already overburdened health care service. Mucorales is a saphrophytic fungi causes rhinocerebral infection involving nasal passages, sinuses, oral cavity and brain. It is usually seen in immunocompromised host and in diabetics with poorly controlled blood sugar level. High degree of clinical suspicion is needed to suspect and diagnose mucormycosis. It is a fatal disease because of its angioinvasive pathogenesis and treatment is promptly initiated to salvage mortality and morbidity. Authors report a case of rhino-oculo-cerebral mucormycosis in a middle-aged diabetic patient with severe COVID-19 disease.

Author Biographies

Sudhir K. Atri, Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India

Senior Professor, Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak

Sanjay Fotedar, Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India

Associate Professor, Department of Medicine, Pt. B.D. Sharma PGIMS, Rohtak

Homdutt ., Department of Medicine, Sanjay Gandhi Memorial Hospital, Magolpuri, Delhi, India

Senior Resident

Department of General Medicine

Vinay Malik, Department of Radiology, Healthmap Diagnostics, Rohtak, Haryana, India

Consultant Radiologist

Parul Punia, Department of Microbiology, Pt. B.D. Sharma PGIMS, Rohtak, Haryana, India

Associate Professor, Department of Microbiology, Pt. B.D. Sharma PGIMS, Rohtak

References

Maini A, Tomar G, Khanna D, Kini Y, Mehta H, Bhagyasree V. Sino-orbital mucormycosis in a covid -19 patient: A case report. Int J Surg Case Rep. 2021;82:105957.

Chander J, Kaur M, Singla N, Punia R, Singhal S, Atrij AG. Mucormycosis battle with the deadly enemy over five year period in India. J Fungi (Basel). 2018;4:46.

Werthman-Ehrenreich A. Mucormycosis with orbital compartment syndrome in apayient with COVID-19. Am J Emerg Med. 2021;42:264.

Veisi A, Bagheri A, Eshaghi M, Rikhtehgar MH, Kanavi MR, Farjad R. Rhino-orbital mucormycosis during steroid therapy in COVID-19 patients: a case report. Eurp J Ophthalmol. 2021;11206721211009450.

Mehta S, Pandey A. Rhino-Orbital Mucormycosis associated with Covid-19. Cureus. 2020;12:e10726.

Alekseyev K, Didenko L, Chaudhary B. Rhinocerebral Mucormycosis and COVID-19. Pneumonia J Med Cases. 2021;12:85-9.

Brunet K, Rammaret B, Mucomycosis treatment. Recommendations and perspectives. J Mycol Med. 2020;30:101007.

Rammaert B, Lanternier F, Poiree S, Kania R, Lortholary O. Diabetes and murcormycosis: a complex interplay Diiab Metab. 2012;38:193-204.

Ge S, Paaskar S, Shetty VP. Rhhinomaxillary mucormycosis with cerebral extension. J Oral Maxillofac Pathol. 2009;50:290-6.

Mignogna MD, Fortuna G, Leuci S. Mucormycosis in immunocompetent patients: a case series of patients with maxillary sinus involvement and critical revive of literature. Int J Infect Dis. 2011;15:533-40.

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Published

2022-05-27

How to Cite

Atri, S. K., Fotedar, S., ., H., Malik, V., & Punia, P. (2022). COVID-19 pneumonia and mucormycosis a new challenging duo- rhino-occulo-cerebral mucormycosis: a case report. International Journal of Research in Medical Sciences, 10(6), 1374–1378. https://doi.org/10.18203/2320-6012.ijrms20221498

Issue

Section

Case Reports