DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20221492

Evaluation of effective anti-tumarogenic dose of ethanolic leaves extract of Moringa oleifera Lam. in Ehrlich ascites carcinoma bearing mice

Ramanath B., Abhay John

Abstract


Background: To evaluate the optimum protective and curative antitumarogenic dose of the ethanolic leaves extract of Moringa oleifera Lam (ELMO). variety against Ehrlich ascetic carcinoma (EAC) cells.

Methods: The protective and curative antitumor activity of ELMO was evaluated against the EAC tumor model. The activity was assessed using survival time and increase in life span.

Results: Oral administration of all the doses of treated ELMO shown significantly increased in mean survival time and percent of life span, in that 500 mg/kg body wt. shown highest significance.

Conclusions: ELMO treated 500 mg/kg body wt. possesses showed antitumor activity.


Keywords


ELMO, Protective, Curative dose, MST, %ILS, EAC

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References


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