Published: 2022-10-28

Hepatic undifferentiated embryonal sarcoma as a cause of acute abdomen

Karina Sánchez-Reyes, Marco P. Tovar-Ferrer, Erik D. Álvarez-Sores, Javier Cerrillo-Ávila, Estrella Aguilar-Hernández, Rocio L. Arreola-Rosales, Tania Gamboa-Jiménez, José L. Martínez Ordaz


Primary liver sarcoma represents less than 1% of all primary liver tumors. Hepatic undifferentiated embryonal sarcoma (HUES) is included in the histologic group of primary liver sarcomas. HUES is a rare malignant liver tumor with a low incidence in the adult population. At moment there is no tumor marker that increases suspicion or diagnosis Early diagnosis is key to rise the possibilities of long-term survival. It has currently improved its prognosis through multidisciplinary management with surgical resection and chemotherapy. This case report presents a 20-year-old female patient with acute abdomen and anemic syndrome secondary to spontaneous rupture of a HUES requiring medical management initially based on resuscitation and arterial embolization with subsequent surgical resection.


HUES, Hepatic bisegmentectomy, Hepato-splenicscintigraphy

Full Text:



Kim SR, Kim J, Seung J, Joh GJ. Surgical treatment outcomes of primary hepatic sarcomas: A single center experience. World J Hepatol. 2021;13(5):584-94.

Luna JY, García L. Sarcoma hepático roto como causa de abdomen agudo. Revista española de enfermedades digestivas. Revista Española de Enfermedades Digestivas. 2019;111(10):814-5.

Cavalcanti AL, Et. AY. Surgical experience of adult primary hepatic Adult primary liver sarcoma: systematic review. Rev Col Bras Cir. 2015;47:e20202647.

Lin YC, Concejero C, Chien A, Ying C, Chi FC. Surgical experience of adult primary hepatic sarcomas. World J Surg Oncol. 2015;13:87.

Jiménez ML, Burgueño A, Herraiz J, Rodríguez M, Orón S, Ibars MP et al. Sarcoma Indiferenciado (embrionario) de hígado del adulto: informe de un caso y revisión de la literatura médica. Gastroenterol Hepatol. 2008;31(1):12-7.

Huang J. Undifferentiated Embryonal Sarcoma of the Liver in Adults. In: Sergi CM, editor. Liver Cancer. Brisbane (AU): Exon Publications. 2021;9.

Putra JY, Ornvoid K. Undifferentiated Embryonal Sarcoma of the Liver. A Concise Review. Arch Pathol Lab Med. 2015;139(2):269-73.

Thombare PV, Shah M, Doshi K, Verma H, Patkar GD. Undifferentiated embryonal sarcoma of liver: Paradoxical imaging appearance. Radiol Case Rep. 2020;15(7):1095-8.

Yu RC, Jiang Y, Hong B, Fang LX. Primary hepatic sarcomas: CT findings. Eur Radiol. 2008;18(10):2196-205.

Nykänen TP, Sallinen E, Mäkisalo V, Nordin HA, Kylänpää L et al. Transcatheter arterial embolization in hepatic tumor hemorrhage. Scandinavian J Gastroenterol. 2019;54(7):917-24.

Techavichit PM, Himes P, Abbas R, Goss R, Vasudevan JS. Undifferentiated embryonal sarcoma of the liver (UESL). J Pediatr Hematol Oncol. 2016;38(4):261-8.

Pérez VM, Ponce T, Rodrígues M C. Sarcoma hepático embrionario indiferenciado: reporte de caso y revisión de la literatura. Bol Med Hosp Infant Mex. 2021;78(6):Méxiconov./dic.

Bowen S, Chapman T, Borgman J, Miyaoka R, Kinahan P, Liou I et al. Measuring total liver function on sulfur colloid SPECT/CT for improved risk stratification and outcome prediction of hepatocellular carcinoma patients. EJNMMI Res. 2016;6:57.