Published: 2022-10-28

A case report on a rare presentation of Aeromonas hydrophila

Nikhil Teja Kambhampati, Vasant Pazhayannoor Kurupath, Subhash Chandra, Abhishek C. Menon


The genus Aeromonas is a member of the family Vibrionaceae. Aeromonas hydrophila is a water-dwelling, gram-negative rod-shaped bacterium, associated with diarrheal illness and less commonly, bone and soft tissue infections, especially among immunocompromised patients. Here we reported a rare presentation of A. hydrophila causing septicemia, septic arthritis, and osteomyelitis in an immunocompetent patient. A 35-year-old female, known hypothyroidism, presented with low back pain for one and half months and left side hip pain radiating to the left lower limb for one month. While in the hospital, she subsequently developed overwhelming sepsis secondary to septic arthritis and osteomyelitis. Which was secondary to a multidrug-resistant strain of A. hydrophila. Despite broad-spectrum antibiotics and aggressive surgical management, she had a recurrence of the infection. Aeromonas species infection in both immunocompetent and immunocompromised patients may result in high morbidity and mortality. This organism is highly virulent and multidrug-resistant. So early diagnosis and early administration of antibiotics would give better outcomes.


Aeromonas hydrophila, Antibiotic resistance, Bone and soft tissue infection

Full Text:



Bijayani B, Sandeep B, Purva M, Sushma S, Maneesh S. Post-traumatic skin and soft tissue infection due to Aeromonas hydrophila. Indian J Crit Care Med. 2011;15(1):49-51.

Janda JM, Abbott SL. The genus Aeromonas: taxonomy, pathogenicity, and infection. Clin Microbiol Rev. 2010;23(1):35-73.

Kenji O, Fumihiro S, Masaki Y, Atsushi M, Ichiro M, Hidefumi H. Severe sepsis caused by Aeromonas hydrophila in a patient using tocilizumab: a case report. J Med Case Rep. 2011;5:499.

Ko WC, Lee HC, Chuang YC, Liu CC, Wu JJ. Clinical features and therapeutic implications of 104 episodes of monomicrobial Aeromonas bacteremia. J Infect. 2000;40(3):267-73.

Mandell GL, Bennett JE, Dolin R. Mandell, Douglas and Bettett's Principles and practice of infectious diseases. 6th ed. Philadelphia: Elsevier Churchill Livingstone; 2005.

Ugarte-Torres A, Perry S, Franko A, Church DL. Multidrug-resistant Aeromonas hydrophila causing fatal bilateral necrotizing fasciitis in an immunocompromised patient: a case report. J Med Case Rep. 2018;12:326.

Regmi A, Khanal P. Aeromonas hydrophila Infection in an Immunocompetent Patient Leading to Necrotizing Fasciitis. J Infect Dis Epidemiol. 2020;6:109.

Padmaja K. Sepsis due to Aeromonas hydrophila. Int J Infect Control. 2013;9:4.

Yumoto T, Ichiba S, Umei N, Morisada S, Tsukahara K, Sato K, Ugawa T, et al. Septic shock due to Aeromonas hydrophila bacteremia in a patient with alcoholic liver cirrhosis: a case report. J Med Case Rep. 2014;8:402.