Foeto-placental weight relationship in normal pregnancy and pregnancies complicated by pregnancy induced hypertension and abruption of placentae
Keywords:
Placenta, Pregnancy induced hypertension, Abruption of placentae, Fetal weightAbstract
Background: The aim of this study was to study the effects of pregnancy induced hypertension and abruption of placenta on foeto-placental weight ratio and its comparison with normal group.
Methods: In this comparative study hundred and twenty placentae were collected from labor room and gynecology operation theatre of Liaquat University hospital. Forty placentae from parturient that had pregnancy induced hypertension & forty placentae from parturient with history of Abruption of placenta & forty cases belonged to normal pregnancy (Control group). Fetal weights in all groups were taken along with the weights of placentae and foeto-placental weight was calculated in all groups.
Results: Placental parameter weight and diameter of placenta in abruption of placentae and PIH group when compared with control group show highly significant (P <0.001) difference. The weight of the new born in abruption of placentae and PIH group also differs from control group significantly (P = 0.001). The feto-placental ratio is also significant statically in abruption of placentae but not in PIH.
Conclusion: Both PIH and abruption of placentae are associated with remarkable changes in placenta such as small placental weight and diameter and as a result low birth weight babies and so altered feto-placental ratio.
References
Udainia A, Jain ML. Morphological study of Placenta in pregnancy induced hypertension with its clinical relevance. J Anat Soc India. 2001;50(01):01-6.
Anca M, Anna A, Penn P. The placenta: the lost neuroendocrine organ. Neoreviews. 2010;11:64-77.
Elsasser DA, Ananth CV, Prasad V, Vintzileos AM. Diagnosis of placental abruption: relationship between clinical and histopathological findings. Eur J Obstet Gynecol Reprod Biol. 2010;148(2):125.
Singh S, Gugapriya TS. Micro anatomical analysis of hypertensive placenta. A retrospective case control study. Natl J Clin Anat. 2013;2(1):5-10.
Gupta S, Gupta P. Correlation of placental weight and fetal outcome in pregnancy induced hypertension. Indian J Appl Basic Med Sci. 2012;14:76-82.
Goswami P, Memon S, Pardeep K. Histological and radiological study of calcified placenta. IOSR-JDMS. 2013;7(4):37-41.
Devi CK, Neelam S, Raghupathy NS. The histological findings in human placenta at different gestational ages. IOSR-JDMS. 2013;6(1):29-31.
Sultana S, Hossain GA, Rahman H, Hasan N, Manan S, Zannat S. Gross morphometry of human placenta in eclampsia. Mymensingh Med J. 2006;15(1):10-4.
Rahman MA, Rahman MH, Habib MA, Selimuzzaman SM. Placental changes in eclampia and fetal outcome. Mymensingh Med J. 2007;16(2):191-6.
Sultana S, Hossain GA, Rahman MH, Hasan N, Sultana SZ, Khalil M. Changes of placental diameter thickness and cotyledon in eclampsia. Mymensingh Med J. 2007;16(2):127-31.
Sarwar I, Abbasi A, Islam A. Abruptio placentae and its complications at Ayub teaching hospital Abbottabad. J Ayub Med Coll Abbottabad. 2006;18(1):27-31.
Rahman LA, Hairi NN, Salleh N. Association between pregnancy induced hypertension and low birth weight: a population based case-control study. Asia-Pac J Public Health. 2008;20(2):152-8.
Palaskar PA, Chaudhary KR, Mayadeo NM. Foeto-placental weight relationship in normal pregnancy and preeclampsia-eclampsia: a comparative study. Bombay Hosp J. 2001;43(3):361-3.
Raghunath G, lakshmi V, Shenoy V. A study on the morphology & morphometry of human placenta & its clinical relevance in a population in tamilnadu. J Clin Diagn Res. 2011;5(2):282-6.
Nag U, Chakravarthy VK, Rao DR. Morphological changes in placenta of hypertensive pregnant women. IJRRMS. 2013;3(2):1-4.
Ananth CV, Berkowitz GS, Savitz DA, Lapinski RH. Placental abruption and adverse perinatal utcomes. JAMA. 1999;282(17):1646-51.
Rath G, Garg K, Sud M. Insertion of umbilical cord on the placenta in hypertensive mothers. J Anat Soc India. 2000;49(2):149-52.