Osteofibrous dysplasia of the proximal tibia: an illustrative case report

Sastha K. Sharan, J. K. Giriraj Harshavardahan, Ganesan Ganesan Ram, Sundar Suriyakumar, Pagal Varthi Vijayaraghavan


A 5 years old girl presented 3 years back with pain and swelling over the upper right leg for 2 years duration. X-ray, CT and MRI revealed osteolytic well defined lesion 2.5 × 2 cm in the meta-diaphyseal region of the proximal tibia with pathological fracture of anterolateral cortex. Child underwent thorough curettage of the lesion and the defect was filled with allograft (iliac crest graft) from mother which was harvested in an adjacent operation theatre. The limb was protected with a plaster splint for a period of 3 months. The graft gradually consolidated and new bone formation was apparent by 6 months. Remodelling of the medullary canal occurred at 1 year follow up. Child has been followed up to 3 years (till date) and there is no evidence of recurrence. The case illustrates that osteofibrous dyplasia can be effectively treated by curettage and replacement of defect by allograft from parents. 


Osteolytic, Osteofibrous dyplasia, Curettage

Full Text:



Campanacci M, Laus M. Osteofibrous dysplasia of the tibia and fibula. J Bone Joint Surg [Am]. 1981;63-A:367-75.

Campanacci M. Osteofibrous dysplasia of long bones: a new clinical entity. Ital J Orthop Traumatol. 1976;2:221-37.

Frangenheim P. Angeborene ostitis fibrosa als Ursache einer intrauterinen Unterschenkelfraktur. Arch Klin Chir. 1921;117:22-9.

Keeney GL, Unni KK, Beabout JW, Pritchard DJ. Adamantinoma of long bones: a clinicopathologic study of 85 cases. Cancer. 1989;64:730-7.

Kempson RL. Ossifying fibroma of the long bones. A light and electron microscopic study. Arch Pathol. 1966;82:218-33.

Komiya S, Inoue A. Aggressive bone tumourous lesion in infancy: osteofibrous dysplasia of the tibia and fibula. J Paediatr Orthop. 1993;13:577-81.

Nakashima Y, Yamamuro T, Fujiwara Y, Kotoura Y, Mori E, Hamashima Y. Osteofibrous dysplasia (ossifying fibroma of long bones): a study of 12 cases. Cancer. 1983;52:909-14.

Park YK, Unni K, McLeod RA, Pritchard DJ. Osteofibrous dysplasia: clinicopathologic study of 80 cases. Hum Pathol. 1993;24:1339-47.

Schoenecker PL, Swanson K, Sheridan JJ. Ossifying fibroma of the tibia. J Bone Joint Surg. 1981;63-A:483-8.