Disproportionate rise in serum CA 125 in case of budd chiari syndrome: an unusual presentation

Authors

  • Prasad D. Game Deportment of Medicine, Government Medical College, Nagpur-440009, Maharashtra
  • Madhuri P. Holay Deportment of Medicine, Government Medical College, Nagpur-440009, Maharashtra
  • Satyanarayan Durgam Deportment of Medicine, Government Medical College, Nagpur-440009, Maharashtra
  • Sandeep Kharkar Deportment of Medicine, Government Medical College, Nagpur-440009, Maharashtra

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150340

Keywords:

Budd chiari syndrme, CA 125, Postpartum period

Abstract

Ca 125 is used as a diagnostic and prognostic biomarker for ovarian cancer. The level of CA 125 is also elevated in benign conditions like Budd Chiari syndrome, liver cirrhosis and heart failure. But very high level of CA 125 is rarely associated with benign conditions and this can mislead the physician. Here we present a case of budd chiari syndrome in postpartum period associated with very high level of CA 125 which is an unusual presentation.

References

Gastroenterology Research and Practice, Article: Prevalence of Budd-Chiari Syndrome during Pregnancy or Puerperium: A Systematic Review and Meta-Analysis, 2014. Available at http://www. hindawi.com/journals/grp/aa/839875/ Accessed 30 August 2014.

Santillan A, Garg R, Zahurak ML, et al. Risk of epithelial ovarian cancer recurrence in patients with rising serumCA-125 levels within the normal range. Journal of Clinical Oncology. 2005;23(36):9338–43.

Xiao WB, Liu YL. Elevation of serum and ascites cancer antigen 125 levels in patients with liver cirrhosis. J Gastroenterol Hepatol. 2003;18(11):1315-6.

Zuckerman E, Lanir A, Sabo E, Rosenvald-Zuckerman T, Matter I, Yeshurun D, et al. Cancer antigen 125: a sensitive marker of ascites in patients with liver cirrhosis. Am J Gastroenterol. 1999;94(6):1613-8.

Gastroenterology Research and Practice, The Significance of Serum CA-125 Elevation in Chinese Patients with Primary Budd-Chiari Syndrome: A Multicenter Study, Available at www.hindawi. com/journals/grp/aa/121060/ Accessed 4 December 2014.

Mahmoodi BK, Brouwer JLP, Ten Kate MK, et al. A prospective cohort study on the absolute risks of venous thromboembolism and predictive value of screening asymptomatic relatives of patients with hereditary deficiencies of protein S, protein or antithrombin. Journal of Thrombosis and Haemostasis. 2010;8(6):1193–200.

Dilawari JB, Bambery P, Chawla Y, et al. Hepatic outflow obstruction (Budd-Chiari syndrome): experience with 177 patients and a review of the literature. Medicine. 1994;73(1):21–36.

Downloads

Published

2017-01-10

How to Cite

Game, P. D., Holay, M. P., Durgam, S., & Kharkar, S. (2017). Disproportionate rise in serum CA 125 in case of budd chiari syndrome: an unusual presentation. International Journal of Research in Medical Sciences, 3(8), 2129–2131. https://doi.org/10.18203/2320-6012.ijrms20150340

Issue

Section

Case Reports