Examination stress and its effect on ovulation of female undergraduate students

Authors

  • Nosakhare O. Osakue Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka
  • Charles Chinedum Onyenekwe Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka
  • Joseph Eberendu Ahaneku Department of Chemical Pathology, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka
  • Onyema Athanasius Onyegbule Department of Obstetrics and Gynaecology, Federal Medical Centre, Owerri, Imo state
  • Patrick Osaze Okunoghae Department of Medical Laboratory Science, Faculty of Health Sciences and Technology, Nnamdi Azikiwe University, Awka

DOI:

https://doi.org/10.18203/2320-6012.ijrms20150801

Keywords:

Cortisol, Progesterone, Glucose, Academic, Menstrual cycle, Ovulatory, Blood flow, Anovulation, Serum

Abstract

Background: Students are susceptible to academic stress which is higher during examination period. Academic stress has been found to activate the Hypothalamic-Pituitary-Adrenal axis resulting in increased cortisol and progesterone levels in circulation. This study sets out to investigate the effects of examination stress on ovulation of 32 apparently healthy female students.

Methods: Serum levels of cortisol (µg/dl), glucose (mmol/L) and progesterone (ng/ml) was determined using blood samples collected on day 21 of the menstrual cycle before and after examination.

Results: The result showed significant elevation in pre-examination serum cortisol (15.3 ± 5.9µg/dl) but significant reduction in Progesterone (3.5± 1.5ng/ml) when compared with post-examination mean serum concentrations of cortisol (10.5 ± 5.1µg/dl) and progesterone (4.2 ± 2.6ng/ml) (P<0.001 and P<0.001) respectively. There was no significance difference in glucose level before examination (5.4 ± 0.8mmol/L) and after examination (5.3 ± 0.7mmol/L) P=0.282.

Conclusions: These findings demonstrated that examination triggers stress, which altered progesterone level in female students.

 

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Published

2017-01-14

How to Cite

Osakue, N. O., Onyenekwe, C. C., Ahaneku, J. E., Onyegbule, O. A., & Okunoghae, P. O. (2017). Examination stress and its effect on ovulation of female undergraduate students. International Journal of Research in Medical Sciences, 3(10), 2618–2622. https://doi.org/10.18203/2320-6012.ijrms20150801

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Original Research Articles