Eye of the tiger sign in neurodegeneration with brain iron accumulation: a case report

Sumantro Mondal, Debasish Dey, Tony Ete, Debanjali Sinha, Arijit Nag, Atanu Chakraborty, Amod Prasad


Neurodegeneration with brain iron accumulation (NBIA) is a rare autosomal recessive disorder characterized by abnormal accumulation of ferritin in globus pallidus of brain. Magnetic resonance imaging (MRI) of brain demonstrates a characteristic ‘eye-of-the-tiger’ sign. We describe a case of NBIA in a child with classical clinical and MRI of brain features.


Neurodegeneration with brain iron accumulation, MRI, Eye of the tiger

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