Cord blood parameters change in pregnancy induced hypertension

Authors

  • Purnima Meher Department of Physiology, V.S.S Institute of Medical Science & Research, Burla, Odisha, India
  • Sitanshu Kumar Meher Department of Paediatrics, V.S.S Institute of Medical Science & Research, Burla, Odisha, India
  • Sunil Kumar Jena Department of Physiology, V.S.S Institute of Medical Science & Research, Burla, Odisha, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20171850

Keywords:

Absolute neutrophil count, Hypertension, TPC

Abstract

Background: Pregnancy induced hypertension (PIH) is a multisystem disease of unknown etiology which affects only human beings. It poses several problems to both mother and child. Complications in newborns like intrauterine death (IUD), intrauterine growth retardation (IUGR), perinatal asphyxia, neonatal sepsis and bleeding disorders are associated with toxaemia of pregnancy. To decrease the perinatal morbidity and mortality, babies of hypertensive mothers should be carefully monitored and managed. Aim of this study was to establish the changes in total platelet count, reticulocyte count and absolute neutrophil count of umbilical cord blood in pregnancy induced hypertension as compared to normotensive mothers.

Methods: This case-control study was conducted among 60 subjects including 30 case (diagnosed cases of pregnancy induced hypertension) and 30 control (normotensive pregnant women). The case group was again categorized into three subgroups – gestational hypertension (06), pre-eclampsia (16) and eclampsia (08). In all the subjects, 2 ml of umbilical cord blood anticoagulated with EDTA was collected and haematological tests for reticulocyte count, total platelet count (TPC) and absolute neutrophil count was done.

Results: There was significant decrease in TPC (p<0.01) and absolute neutrophil count (p<0.01), but significant rise in reticulocyte count (p<0.05) in umbilical cord blood of babies born to hypertensive mothers compared to normotensive mothers

Conclusions: From this study, it can be concluded that newborns of hypertensive mothers carry risks for infection and bleeding complications. So, these simple haematological tests can be done at early stage in neonates to reduce possible perinatal morbidities and mortality.

Author Biography

Purnima Meher, Department of Physiology, V.S.S Institute of Medical Science & Research, Burla, Odisha, India

Physiology, PG Student

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Published

2017-04-26

How to Cite

Meher, P., Meher, S. K., & Jena, S. K. (2017). Cord blood parameters change in pregnancy induced hypertension. International Journal of Research in Medical Sciences, 5(5), 2099–2103. https://doi.org/10.18203/2320-6012.ijrms20171850

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Original Research Articles