Trial of vitamin D supplementation to prevent asthma exacerbation in children

Authors

  • Elango Krishnan Department of Paediatrics, KAPV Government Medical College, Trichy, Tamil Nadu, India
  • Venmugil Ponnusamy Department of Paediatrics, KAPV Government Medical College, Trichy, Tamil Nadu, India
  • Sathiya Priya Sekar Department of Paediatrics, KAPV Government Medical College, Trichy, Tamil Nadu, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20172479

Keywords:

Asthma, Children, Exacerbation, Vitamin D, Vitamin D supplementation

Abstract

Background: To assess the level of vitamin D in children with bronchial asthma and to study the effects of vitamin D supplementation in asthmatic children who had vitamin D deficiency in terms of asthma control test score and Number of exacerbations.

Methods: This interventional study was conducted in Department of Paediatrics, KAPV Government medical college, Trichy, Tamil Nadu, India from September 2016 to February 2017. 96 asthmatic children of age group 5-12 years who attended outpatient department and admitted in ward for asthma exacerbation were selected. After assessing their Vitamin D level, Vitamin D supplementation given along with standard treatment for asthma. Outcomes measured were ACTS (Asthma control test score), number of emergency room visits, number of hospital admissions and reliever medication use.

Results: Out of 96 children, 83 (86.4%) children had vitamin D deficiency. There was significant correlation between vitamin D level and absolute eosinophil count (p-value-0.037), asthma severity (p-value<0.001) and asthma control (p-value<0.001). Significant reduction in emergency room visits, (p-value<0.001) reliever medication use (p-value<0.001) and improvement in asthma control test score (p-value-0.008) occurs after vitamin D supplementation.

Conclusions: There is a significant correlation between vitamin D level, asthma severity and its control. Asthma exacerbation in terms of emergency room visits and reliever medication use were further reduced by vitamin D supplementation.

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Published

2017-05-27

How to Cite

Krishnan, E., Ponnusamy, V., & Sekar, S. P. (2017). Trial of vitamin D supplementation to prevent asthma exacerbation in children. International Journal of Research in Medical Sciences, 5(6), 2734–2740. https://doi.org/10.18203/2320-6012.ijrms20172479

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Original Research Articles