Clinical, socio-demographic profile and outcome of neurocysticercosis in children: a hospital based study
DOI:
https://doi.org/10.18203/2320-6012.ijrms20172098Keywords:
Neurocysticercosis, Ring enhancing lesion, SeizureAbstract
Background: Neurocysticercosis (NCC) is perhaps the most common parasitic infection of human nervous system. The objective of this study was to study the spectrum of clinical, socio-demographic profile and treatment outcome of 60 paediatric neurocysticercosis cases over a mean duration of two years from September 2006-August 2008.
Methods: Diagnosis was made mainly on the basis of clinical features, ring enhancing lesions on Computed Tomography scan of brain and exclusion of other causes. Patients were treated with Albendazole for 28 days, Prednisolone and anticonvulsant.
Results: 10-14 years was the most affected age group with no sex predilection. Seizure was the most common initial presentation (86.66%) followed by headache and vomiting. Generalized tonic clonic seizure was the most common type of seizure. Four patients returned with relapse.
Conclusions: Neurocysticercosis is a disease of lower socioeconomic group with poor sanitation and poor hand hygiene. Generalized tonic clonic seizure is the main presentation. Anticysticercal therapy has a good outcome.
References
Blanton R. Cysticercosis. In: Kliegman RM, Jenson HB, Behrman RE, Stanton BF, editors. Nelson Textbook of Paediatrics. Philadelphia: Saunders Elsevier; 2007:1514-1516.
Bhattacharjee S, Biswas P. Childhood seizure - a case of neurocysticercosis involving left parietal lobe. Turk Noroloji Dergisi. 2011;17:167-70.
Antoniuk S, Bruck I, Santos LH, Souza LP, Fugimura S. Neurocysticercosis in children: clinical study and follow up of 112 patients. Rev Neurol. 2006;42 Suppl 3:S97-101.
Del Brutto OH, Rajshekhar V, White AC, Tsang VC, Nash TE, Takayanagui OM, et al. Proposed diagnostic criteria for neurocysticercosis. Neurol. 2001;57:177-83.
White AC, Weller PF, Cestodes. In: Kasper DL, Fauci AS, Longo DL, Braunwald E, Hauser SL, Jameson JL et al, editors. Harrison’s Principles of Internal Medicine. New York: McGraw Hill; 2008:1337-8.
Singhi P, Ray M, Singhi S, Khandelwal N. Clinical spectrum of 500 children with neurocysticercosis and response to albendazole therapy. J Child Neurol. 2000;15:207-13.
Singhi P. Neurocysticercosis. Ther Adv Neurol Disord. 2011;4:67-81.
Gauchan E, Malla T, Basnet S, Rao KS. Variability of presentations and CT-scan findings in children with neurocysticercosis. Kathmandu Univ Med J. 2011;9:17-21.
Prasad R, Mishra OP, Mishra SP, Upadhyay RS, Singh TB. Oxidative stress in children with neurocysticercosis. Pediatr Infect Dis J. 2012;31:1012-5.
Kalra V, Sethi A. Childhood neurocysticercosis - Epidemiology, diagnosis and course. Acta Paediatr Jpn. 1992;34:365-70.
Carpio A. Neurocysticercosis: An update. Lancet Infect Dis. 2002;2:751-62.
Kalra V. Neurocysticercosis. In: Parthasarathy A, Menon PS, Agarwal RK, Choudhury P, Thacker CN, Ugra D, et al, editors. IAP Textbook of Paediatrics. New Delhi: Jaypee Brothers Medical Publishers; 2009:469-70.