DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20164551

A cross-sectional study of impaired glucose tolerance amongst undergraduate medical students

Kavisha Singh, Aniruddha A. Malgaonkar, Dinesh R. Samel

Abstract


Background: Diabetes is an important chronic disease both in terms of prevalence and associated morbidity and early mortality. Mortality rates in diabetics are two- to threefold higher than those without diabetes. Type 2 Diabetes Mellitus is preceded by a period of abnormal glucose homeostasis and hence early diagnosis is important in decreasing this morbidity and mortality. The oral glucose tolerance test (OGTT) is currently the gold standard for the diagnosis of diabetes.

Methods: This cross sectional single observer study was conducted amongst all the undergraduate students and interns of a municipal medical college to assess the point prevalence of impaired glucose tolerance and the factors predisposing to the same. After necessary permissions, participants giving written informed consent were interviewed and participants were subjected to an oral glucose tolerance test (OGTT) and their heights, weights were measured.

Results: None of the participants had an increased fasting blood glucose but 30 min, 60 min and 90 min post OGTT blood glucose levels were increased in 9 (11.84%) participants and 120 min post OGTT blood glucose was increased in 15 (19.73%) participants. Increase in Body Mass Index (BMI) shows a positive correlation with fasting (r=0.155) and 120 min post OGTT blood glucose (r=0.042). Increase in weekly junk food servings shows a positive correlation with fasting (r=0.014), 90 min (r=0.004) and 120 min post OGTT blood glucose (r=0.009).

Conclusions: Impaired glucose tolerance was present in a substantial number of non-diabetic students and had a correlation with BMI, exercise and junk food intake.

Keywords


Impaired glucose tolerance, Latent diabetes, Medical Students

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References


Zgibor J, Dorman J. Diabetes, Wallace/Maxcy-Rosenau-Last. Public Health and Preventive Medicine. 15th Edition. 1101-12.

Phillips PJ. Oral glucose tolerance testing, Emergency Care. 2012;41(6):391-3.

Diabetes – Facts and Figures, International Diabetes Federation. Available at: http://www.idf.org/ about-diabetes/facts-figures Last Accessed: 29/10/2016.

Harrison’s Principles of Internal Medicine, Chapter-334, 18th Edition. 2012.

Parkin C, Davidson J. Value of self-monitoring blood glucose Pattern Analysis in improving diabetes outcome, J. Diabetes Sc Technology. 2009;3(3):500-8

Sinha R, Fisch G, Teague B, Tamborlane WV, Banyas B, Allen K, et al. Prevalence of impaired glucose tolerance among children and adolescents with marked obesity. N Engl J Med. 2002;346(11):802-10.

Valdez R, Yoon PW, Liu T, Khoury MJ. Family history and prevalence of diabetes in the U.S. population: the 6-year results from the National Health and Nutrition Examination Survey (1999-2004). Diabetes Care. 2007;30(10):2517-22.

Ganz ML, Wintfeld N, Li Q, Alas V, Langer J, Hammer M. The association of body mass index with the risk of type 2 diabetes: a case-control study nested in an electronic health records system in the United States. Diabetol Metab Syndr. 2014;6(1):50.

Hopper M, Koch C. A preliminary study on the variability of blood glucose following meal consumption as it relates to differences in oral glucose tolerance in young adults. Nutr Health. 2015;22(3-4):197-214.

Higaki Y, Shono N, Nishizumi M. Decreased physical fitness in borderline glucose tolerance men. Environ Health Prev Med. 1998;2(4):177-82.

Manson JE, Rimm EB, Stampfer MJ, Colditz GA, Willett WC, Krolewski AS, et al. Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet. 1991;338(8770):774-8.

Ramchandani N, Cantey-Kiser JM, Alter CA, Brink SJ, Yeager SD, Tamborlane WV, et al. Self-reported factors that affect glycemic control in college students with type 1 diabetes. Diabetes Educ. 2000;26(4):656-66.

Zhou X, Pang Z, Gao W, Wang S, Zhang L, Ning F, et al. Performance of an A1C and fasting capillary blood glucose test for screening newly diagnosed diabetes and pre-diabetes defined by an oral glucose tolerance test in Qingdao, China. Diabetes Care. 2010;33(3):545-50.

Davidson MB, Schriger DL, Peters AL, Lorber B. Revisiting the Oral Glucose Tolerance Test Criterion for the Diagnosis of Diabetes. J Gen Int Med. 2000;15(8):551-5.

Huang TT, Shimel A, Lee RE, Delancey W, Strother ML. Metabolic Risks among College Students: Prevalence and Gender Differences. Metab Syndr Relat Disord. 2007;5(4):365-72.