Schwannoma in oropharynx: a rare site posing diagnostic challenge

Authors

  • Deepshikha Rana Department of Pathology, ESIC Medical College, Faridabad, Haryana, India
  • Sujata Raychaudhuri Department of Pathology, ESIC Medical College, Faridabad, Haryana, India
  • Nimisha Sharma Department of Pathology, ESIC Medical College, Faridabad, Haryana, India

DOI:

https://doi.org/10.18203/2320-6012.ijrms20174972

Keywords:

Benign, Neurogenic, Oropharynx

Abstract

Schwannomas are benign nerve sheath tumors. These arise from Schwann cells of the neural sheath. Intra oral region is a relatively uncommon site of these tumors. They are solitary, slow growing, smooth surfaced, usually asymptomatic, and encapsulated tumors, about 25% of all schwannomas are located in the head and neck, but only 1% show intraoral origin. A 22-year-old female came with dysphagia since, 3 years. FNAC was not feasible and so excision biopsy of the lesion was performed. Histopathology revealed schwannoma like picture and it was confirmed with diffuse S-100 positivity on immunohistochemistry. Hence, finally confirming schwannoma of the oropharyngeal region. Schwannomas can be found anywhere in the body but a quarter of all occur in the head and neck region. Intraorally its percentage is only 1% with tongue being the commonest. Pharyngeal presentations of schwannoma are rare. Schwannomas are benign tumors having excellent prognosis. Basically, this case report is important as these very rarely occur in the oropharyngeal region and it’s a must to consider them in the differential diagnosis of lesions at this site.

References

Kao G. Neurilemoma.eMedicine.com Available at http://emedicine.medscape.com/article/ 1058342­overview # a 0104 2013, Updated January 12, 2012.

Lollar KW, Pollak N, Liess BD, Miick R, Zitsch RP. Schwannoma of the hard palate. Americ J Otolaryngol. 2010;31(2):139-40.

Jadwani S, Bansod S, Mishra B. Intraoral schwannoma in retromolar region. J Maxillofacial and oral surg. 2012;11(4):491-4.

de Bree R, Westerveld GJ, Smeele LE. Submandibular approach for excision of a large schwannoma in the base of the tongue. European archives of oto-rhino-laryngology. 2000;257(5):283-6.

Williams HK, Cannell H, Silvester K, Williams DM. Neurilemmoma of the head and neck. British J oral and maxillofacial surg. 1993;31(1):32-5.

Lucas RB. Pathology of tumors of the oral tissues. 4ºEd. Edinburgh: Churchill Livingstone. 1984.

Enzinger IM, Weiss SW. Soft tissue tumours. St Louis: MO Mosby. 1995:821-50.

Weiss SW. Enzinger and Weiss's soft tissue tumors. Malignant soft tissue tumora of uncertain type. 2001:1538-45.

Bildirici K, KEçIK C, DüNDAR E, Agikalin MF. Schwannoma (neurilemmoma) of the palatine tonsil. Otolaryngology--Head and Neck Surgery. 2002;126(6):693-4.

López-Jornet P, Bermejo-Fenoll A. Neurilemmoma of the tongue. Oral Oncology Extra. 2005;41(7):154-7.

Das Gupta TK, Brasfield RD. Solitary schwannoma. Ann Surg. 1976;171(3):419.

Wright BA, Jackson D. Neural tumors of the oral cavity: a review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1980;49(6):509-522.

Requena L, Sangueza OP. Benign neoplasms with neural differentiation: a review. Am J Dermatopathol. 1995;17(1):75-96.

Schnitt SJ, Vogel H. Diagnostic value of immunoperoxidase staining for epithelial membrane antigen. Am J Surg Pathol. 1986;10(9):640-9.

Enoz M, Suoglu Y, Ilhan R. Lingual schwannoma. J Cancer Res Therapeut. 2006;2(2):76.

Downloads

Published

2017-10-27

How to Cite

Rana, D., Raychaudhuri, S., & Sharma, N. (2017). Schwannoma in oropharynx: a rare site posing diagnostic challenge. International Journal of Research in Medical Sciences, 5(11), 5066–5068. https://doi.org/10.18203/2320-6012.ijrms20174972

Issue

Section

Case Reports