Bronchial carcinoid in children

Surendran Aneeshkumar, L. Sundararajan, T. Sunder, Ayesha Shahnaz


Bronchial carcinoids (BCs) are uncommon, slow growing, low-grade malignant neoplasm comprising 0.5-2.5% of all primary lung cancers. Although BC’s in childhood often have an endobronchial location causing airway obstruction, they are frequently misdiagnosed as benign conditions, resulting in a delay in definitive diagnosis and treatment. Lung sparing surgery should be done whenever possible, more so in children, for better quality of life and minimizing skeletal abnormality which follows pneumonectomy. We present two cases of bronchial carcinoid in young children.


Bronchial carcinoid, Lung sparing surgery, Pneumonectomy

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Bhatia K, Ellis S. Unusual lung tumours. An illustrated review of CT features suggestive of this diagnosis. Cancer Imaging. 2006;6:72-82.

Wang LT, Wilkins Jr EW, Bode HH. Bronchial carcinoid tumors in pediatric patients. Chest. 1993;103:1426-8.

Al-Qahtani AR, Di Lorenzo M, Yazbeck S, Endobronchial tumors in children: Institutional experience and literature review. J Pediatr Surg. 2003;38(5):733-6.

Rizzardi G, Marulli G, Calabrese F, Rugge M, Rebusso A, Sartori F, et al. Bronchial carcinoid tumours in children: surgical treatment and outcome in a single institution. Euro J Pediatric Surg. 2009;19(04):228-31.

Fauroux B, Aynie V, Larroquet M, Boccon-Gibod L, le Pointe HD, Tamalet A, et al. Carcinoid and mucoepidermoid bronchial tumours in children. Euro J Pediatrics. 2005;164(12):748-52.

Travis WD, Brambilla E, Muller-Hermelink HK. Tumours of the lung. In: Travis WD, Brambilla E, Muller-Hermelink HK, eds. Pathology and genetics of tumours of the lung, pleura, thymus and heart. WHO health organization classification of tumours. Lyon, France: IARC Press;2004;10.

Buck JL, Sobin LH. Carcinoids of the gastrointestinal tract. Radio Graphics. 1990;10:1081-95.

Fischer S, Kruger M, McRae K, Merchant N, Tsao MS, Keshavjee S. Giant bronchial carcinoid tumors: A multidisciplinary approach. Ann Thorac Surg. 2001;71:386-93.

Erdoğan D, Serhan T, Berker Ö. Bronşiyal karsinoid tümörlerde cerrahi tedavi: 11 yıllık deneyim. Türk Göğüs Kalp Damar Cerrahisi Dergisi. 2014;22(4):795-9.

Gaissert HA, Mathisen DJ, Grillo HC, Vacanti JP, Wain JC. Tracheobronchial sleeve resection in children and adolescents. J Pediatr Surg. 1994;29(2):192-7.

Rizzardi G, Marulli G, Bortolotti L, Calabrese F, Sartori F, Rea F. Sleeve resections and bronchoplastic procedures in typical central carcinoid tumours. The Thoracic and cardiovascular surgeon. 2008;56(01):42-5.

Deslauriers J, Grégoire J, Jacques LF, Piraux M, Guojin L, Lacasse Y. Sleeve lobectomy versus pneumonectomy for lung cancer: a comparative analysis of survival and sites or recurrences. Annals Thoracic Surg. 2004;77(4):1152-6.

Wilkins EW, Grillo HC, Moncure AC, Scannell JG. Changing times in surgical management of bronchopulmonary carcinoid tumor. Ann Thorac Surg. 1984;38:339-44.

Ragusa M, Vannucci J, Cagini L, Daddi N, Pecoriello R, Puma F. Left main bronchus resection and reconstruction. A single institution experience. J Cardiothoracic Surg. 2012;7(1):29.

Gustafsson BI, Kidd M, Chan A, Malfertheiner MV, Modlin IM. Bronchopulmonary neuroendocrine tumors. Cancer. 2008;113(1):5-21.

Filosso PL, Oliaro A, Ruffini E, Bora G, Lyberis P, Asioli S, et al. Outcome and prognostic factors in bronchial carcinoids: a single-center experience. J Thoracic Oncol. 2013;8(10):1282-8.

Phan AT, Öberg K, Choi J, Harrison Jr LH, Hassan MM, Strosberg JR, et al. NANETS consensus guideline for the diagnosis and management of neuroendocrine tumors: well-differentiated neuroendocrine tumors of the thorax (includes lung and thymus). Pancreas. 2010;39(6):784-98.

Darling GE, Allen MS, Decker PA, Ballman K, Malthaner RA, Inculet RI, Jones DR, McKenna RJ, Landreneau RJ, Rusch VW, Putnam JB. Randomized trial of mediastinal lymph node sampling versus complete lymphadenectomy during pulmonary resection in the patient with N0 or N1 (less than hilar) non–small cell carcinoma: Results of the American College of Surgery Oncology Group Z0030 Trial. J Thoracic Cardio Surg. 2011;141(3):662-70.

Nussbaum DP, Speicher PJ, Gulack BC, Hartwig MG, Onaitis MW, D’Amico TA, Berry MF. Defining the role of adjuvant chemotherapy after lobectomy for typical bronchopulmonary carcinoid tumors. Annals thoracic Surg. 2015;99(2):428-34.