DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20180289

5-year analysis of thyroidectomies; a retrospective clinicopathological assessment of papillary carcinoma of thyroid in a coastal urban area

Ahmed Pervez, Pranank Kakarla, Magesh Chandran, Asha Reddy

Abstract


Background: The aim of our study was to analyse thyroidectomies done past 5 years on a clinico pathological basis. Additionally, we also wanted to study the presence and characteristics of papillary carcinoma of thyroid.

Methods: Retrospective analysis of 57 patients who underwent thyroidectomy from 2012 to 2017 performed by Department of General Surgery of Sri Ramachandra Medical College (Chennai, India) was done and checked for statistical significance.

Results: In this 5-year study of 57 thyroidectomies, 17 patients had papillary carcinoma of thyroid, 1 patient had anaplastic carcinoma and another patient had a thyroid metastasis with unknown primary. The nonmalignant 38 patients were studied separately. Regarding malignancy, 29.4% had micro carcinoma. 35.3% were in Stage I. 94.1% were in Grade I, 94.1% had no angioinvasion. 15 patients (88.2%) had negative capsule invasion and negative lympho vascular invasion. 4 patients (23.5%) had extra thyroid extension. The observed difference in the characteristics were statistically not significant (p>0.05). The odds ratio for micro carcinoma of thyroid was 0.364. Most common clinical diagnosis among patients with benign disease was multinodular goiter and 16 (40%) patients had total thyroidectomy. 82.5% of patients had microscopic nodules on histopathology. The association between the surgery type and clinical diagnosis was statistically significant (p<0.001).

Conclusions: Statistical significance was noted between surgery type and clinical diagnosis. Papillary carcinoma of thyroid is not rare even in non endemic areas. The odds ratio for micro carcinoma thyroid is not significant but it does exist and post surgery, regular follow up is important.


Keywords


Clinicopathological Analysis, Papillary Carcinoma, Thyroidectomy

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