Clinicopathological study of benign ovarian tumuors
DOI:
https://doi.org/10.18203/2320-6012.ijrms20183263Keywords:
Dragging pain, Mucinous cystadenoma, Mature cystic teratoma, Pan hysterectomyAbstract
Background: The incidence of ovarian tumor amongst gynecological admissions have been reported to vary from 1-3 %. About 75% of these tumors have been found to be benign. Ovarian malignancies represent the greatest clinical challenge of all the gynecological malignancies. During the reproductive years most of the ovarian tumors encountered are benign. About 2/3 of the ovarian tumors are encountered in this group only. The chance that an ovarian tumor is malignant in a patient younger than 45 years is 1 in 15. The differentiation of the benign from malignant tumors can go wrong even with imaging modalities.CA125 along with ultrasound are useful in differentiating benign from malignant tumors. Histopathological examination is gold standard for diagnosis of ovarian neoplasm.
Methods: The present study includes consecutive cases of histopathologically proven ovarian tumors of 3 years from June 2010 to May 2013 reported by the Department of Pathology of our tertiary care center. It includes total 150 cases. After careful study of gross findings, appropriate bits were taken from received ovarian specimen, followed by routine paraffin processing to make H and E stained slides. Special stains were used wherever needed.
Results: Majority of the cases 91 (60.67%) were benign, 53 (35.33%) were malignant and 6 (4.0%) were borderline. Surface epithelial tumours were the most common type (68.13%) of ovarian neoplasm in this study. Most of tumours in our study occurred in the age group of 21-40 years. Mucinous cystadenomas were most common benign surface epithelial tumour and most common benign tumors overall. There were 22 cases of benign germ cell tumor, all were mature teratoma. All the sex-cord stromal tumours were diagnosed in women older than 40 years. Most common benign lesion in our study is surface epithelial tumour and in age group of 21-40 years. 84% patients studied had symptoms at presentation, out of which 26% of patient presented with dull/dragging pain. Pan hysterectomy was the most common procedure for surgical management.
Conclusions: Most of ovarian neoplasm are benign with mucinous cystadenoma being commonest entity. Commonest age group is 21-40 years. Commonest benign germ cell tumor is Mature cystic teratoma. Commonest clinical symptom is dull/dragging pain. Pan hysterectomy was the most common procedure for surgical management.
References
Berek JS. Berek and Novak’s Gynecology. 15th edition, Lippincott Williams and Wilkins, 2011.
Jones HW, Rock JA. Te Linde's operative gynecology. 10th Edi. Lippincott Williams & Wilkins; 2011.
Timmerman D1, Bourne TH, Tailor A, et al. A comparison of methods for preoperative discrimination between malignant and benign adnexal masses: the development of a new logistic regression model. Am J Obstet Gynecol. 1999 Jul;181(1):57-65.
Kumar P, Jeffcoate’s MN. Principles of gynecology. New Delhi: 7th edi. Jaypee Brothers Medical Publishers. 2008:617-24.
Ahmad Z, Kayani N, Hasan SH, Muzaffar S, Gill MS. Histological pattern of ovarian neoplasma. J Pak Med Associa. 2000;50(12):416-9.
Gupta N. Retrospective and prospective study of ovarian tumors and tumor like lesions. Ind J Patho Micro. 2007;50(3):525-7.
Swamy GG, Satyanarayana N. Clinicopathological analysis of ovarian tumours-A study on five years samples. Nepal Med Coll J. 2010 Dec;12(4):221-3.
Zaman S, Majid S, Hussain M, Chughtai O, Mahboob J, Chughtai S. A retrospective study of ovarian tumours and tumour-like lesions. J Ayub Med Coll Abbottabad. 2010 Mar 1;22(1):104-8.
Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumours: a study of 282 cases. J Ind Med Associa. 2002 Jul;100(7):420-3.
Jha R, Karki S. Histological pattern of ovarian tumors and their age distribution. Nepal Med Coll J. 2008 Jun;10(2):81-5.
Shah S. Incidence and management of ovarian tumors. Bombay Hosp J. 2008;50(1):81-5.
Wasim T, Majrroh A, Siddiq S. Comparison of clinical presentation of benign and malignant ovarian tumours. JPMA. 2009 Jan 1;59(1):18.
Yasmin S, Yasmin A, Asif M. Clinicohistological pattern of ovarian tumours in Peshawar region. J Ayub Med Coll Abbottabad. 2008 Dec 1;20(4):11-3.
Srinivas K, Babu H, Malini KV. Retrospective study of clinical and pathological features of benign ovarian tumors. Sch J App Med Sci. 2015;3(3A):1046-50.
