Transfusion related acute lung injury: a case report

Authors

  • Javier Alcazar Castro Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
  • Alejandro Zárate Aspiros Anesthesiology Service, General Hospital of CDMX, Mexico
  • Elias N. Andrade Cuellar Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
  • Brenda M. Álvarez Pérez Department of Cardiac Electrophysiology Clinic and Arrhythmias, General Hospital of CDMX, Mexico
  • Alan Isaac Valderrama Treviño Laboratory of Experimental Immunotherapy and Tissue Engineering, Faculty of Medicine, UNAM, CDMX, Mexico
  • Juan J. Granados Romero Department of General Surgery, General Hospital of Mexico, CDMX, Mexico
  • Rodrigo Banegas Ruiz Service of Hand Surgery and Microsurgery, Rehabilitation Hospital, Luis Guillermo Ibarra Ibarra, CDMX, Mexico
  • Baltazar Barrera Mera Department of Physiology, Faculty of Medicine, UNAM, CDMX, Mexico

DOI:

https://doi.org/10.18203/2320-6012.ijrms20185396

Keywords:

Acute lung injury, Anaesthesiology, Blood transfusion, Transfusion

Abstract

Transfusion Related Acute Lung Injury (TRALI) is one of the most serious complications of blood transfusion. All blood components have been implicated and most often those that contain plasma. The diagnosis is based fundamentally on the integration of clinical, radiological and gasometry elements, once the rest of the possible causes of acute lung injury have been ruled out. The differential diagnosis of a patient who develops a sudden pattern of respiratory failure after a transfusion of blood products must include hemodynamic overload, anaphylactic reaction, bacterial contamination of transfused blood products, haemolytic transfusion reaction and TRALI. Author presented the clinical case of a 33-year-old female patient with grade III hypovolemic shock due to a ruptured ectopic pregnancy, reanimated with crystalloid solutions, globular packages and fresh frozen plasma. The patient developed TRALI for what was managed with ventilatory and hemodynamic support in ICU.

References

Tariq M, Dhanani Z, Abbas Q, Jurair H, Mahar FK, Haque A. Transfusion-related acute lung injury in a paediatric intensive care unit of Pakistan. JAMC. 2017;29(4):702.

Álvarez P, Carrasco R, Romero-Dapueto C, Castillo RL. Transfusion-related acute lung injured (trali): current concepts. Open Res Med J. 2015;9:92-6.

Marik PE, Corwin HL. Acute lung injury following blood transfusion: expanding the definition. Critical Care Med. 2008;36(11):3080-4.

Kumar R, Sedky MJ, Varghese SJ, Sharawy OE. Transfusion related acute lung injury (TRALI): a single institution experience of 15years. Ind J Hematol Blood Transfusion. 2016;32(3):320-7.

Ariza-Prota MA, Pando-Sandoval A, Budiño T. Transfusion related acute lung injury: An underdiagnosed and dangerous entity. Revista Portuguesa de Pneumologia. 2017;23(3):160-1.

Jaworski K, Maślanka K, Kosior DA. Transfusion-related acute lung injury: a dangerous and underdiagnosed noncardiogenic pulmonary edema. Cardiol J. 2013;20(4):337-44.

Müller MC, Juffermans NP. Transfusion-related acute lung injury: a preventable syndrome?. Expert Rev Hematol. 2012;5(1):97-106.

Peters AL, van de Weerdt EK, Goudswaard EJ, Binnekade JM, Zwaginga JJ, Beckers EA, et al. Reporting transfusion-related acute lung injury by clinical and preclinical disciplines. Blood Transfusion. 2018;16(3):227-34.

Gajic O, Rana R, Winters JL, Yilmaz M, Mendez JL, Rickman OB, et al. Transfusion-related acute lung injury in the critically ill: prospective nested case-control study. Am J Res Critical Care Med. 2007;176(9):886-91.

Aravinthan A, Sen S, Marcus N. Transfusion-related acute lung injury: a rare and life-threatening complication of a common procedure. Clin Med. 2009;9(1):87-9.

Frazier SK, Higgins J, Bugajski A, Jones AR, Brown MR. Adverse reactions to transfusion of blood products and best practices for prevention. Critical Care Nursing Clin. 2017;29(3):271-90.

Vlaar AP, Juffermans NP. Transfusion-related acute lung injury: a clinical review. Lancet. 2013;382(9896):984-94.

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Published

2018-12-26

How to Cite

Alcazar Castro, J., Zárate Aspiros, A., Andrade Cuellar, E. N., Álvarez Pérez, B. M., Valderrama Treviño, A. I., Granados Romero, J. J., Banegas Ruiz, R., & Barrera Mera, B. (2018). Transfusion related acute lung injury: a case report. International Journal of Research in Medical Sciences, 7(1), 285–287. https://doi.org/10.18203/2320-6012.ijrms20185396

Issue

Section

Case Reports