Epidemiology of gastrointestinal cancers in the hospital of Tambohobe Fianarantsoa, Madagascar

Authors

  • Mampionona Ranaivomanana Department of Oncology, University Hospital of Tambohobe, Fianarantsoa, Madagascar
  • Tojo Rafaralahivoavy Department of Radiology, University Hospital of Tambohobe, Fianarantsoa, Madagascar
  • Joelle Razafimahefa Department of Pathology, University Hospital of Tambohobe, Fianarantsoa, Madagascar
  • Anicet M. Rakotovao Department of Visceral Surgery, University Hospital of Tambohobe, Fianarantsoa, Madagascar
  • Rivo A. Rakotoarivelo Department of Infectious Disease, University Hospital of Andrainjato, University of Fianarantsoa Madagascar
  • Hélio S. Razafimahefa Department of Gastroenterology, University Hospital of Andrainjato, University of Fianarantsoa Madagascar
  • Florine Rafaramino Department of Oncology, Joseph Ravoahangy Andrianavalona University Hospital, University of Antananarivo Madagascar

DOI:

https://doi.org/10.18203/2320-6012.ijrms20194289

Keywords:

Epidemiology, Fianarantsoa, Gastrointestinal cancer, Madagascar

Abstract

Background: Gastrointestinal cancers are among the top 10 cancers and causes of cancer death worldwide. Given the absence of cancer registry in Madagascar and absence of epidemiological study of gastrointestinal cancer in the province of Fianarantsoa, our aim was to describe the epidemiological aspect of gastrointestinal cancers at the University Hospital of Tambohobe Fianarantsoa.

Methods: Authors have conducted a descriptive retrospective study over a three-year period from January 1, 2015 to December 31, 2017 at the University Hospital of Tambohobe Fianarantsoa (in oncology, internal medicine and visceral surgery departments). The variables analyzed were age, gender, tumor location.

Results: Authors have collected 74 cases of gastrointestinal cancers. There were 46 males 62.16% and 28 females 37.84%. The mean age was 56.30±12.10 years old. The predominant age groups were 45-55 years. Authors found colorectal cancer in 43%, followed by liver carcinoma in 19%, then pancreatic cancer 14%, esophageal cancer 13%, gastric cancer 8%, duodenum cancer 3%.

Conclusions: Gastrointestinal cancers at the hospital of Tambohobe Fianarantsoa affect young people, especially the male gender with a predominance of colorectal and liver cancer.So, it is important to continue the vaccination against hepatitis viral B infection and to implement a colorectal cancer screening program.

References

Ferlay J, Soerjomataram I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015 Mar 1;136(5):E359-86.

Peghini M, Rajaonarison P, Pecarrere JL, Razafindramboa H, Richard J, Morin D. Epidemiology of digestive tract cancers in Madagascar: contribution of 14000 endoscopies performed at the Soavinandriana hospital centre in Antananarivo Med Afr Noire. 1997;44:518-21.

Hasiniatsy NRE, Ramahandrisoa AVN, Refeno V, Rakoto FA, Rafaramino F. Epidemiological aspects of cancers managed at the military hospital of Antananarivo, Madagascar. Bull Cancer 2017;104(10):902-4.

Diarra M, Konate A, Traore CB, Souchko-Kaya A, Diarra CA, Doumbia-Samake K, Diallo G, Traore HA, Maiga MY. Epidemiology of digestive cancers in hospitals in Bamako. HEGEL. 2012;2(1):12-22.

Horner MJ, Ries LA, Krapcho M, Neyman N, Aminou R, Howlader N, et al. SEER cancer statistics review. National Cancer Institute. 1975;2006. Available at: https://seer.cancer.gov/csr/1975_2014. Accessed 9 April 2018.

Life expectancy at birth. The World Bank; 2017. Available at: https://data.worldbank.org/indicator/sp.dyn.le00.in. Accessed 20 June 2018.

Rakotoniaina JP. Enquête nationale sur le tabagisme chez les jeunes (GYTS) 2008. Available at: http://www.who.int/fctc/reporting/party_reports/madagascar_annex2_GYTS_2008.pdf. Accessed 20 june 2018.

Larsson SC, Permert J, Hakansson N, Naslund I,Bergkvist L, Wolk A. Overall obesity, abdominal adiposity, diabetes and cigarette smoking in relation to the risk of pancreatic cancer in two Swedish population-based cohorts. Br J Cancer. 2005;93:1310-5.

Hannan LM, Jacobs EJ, Thun MJ. The association between cigarette smoking and risk of colorectal cancer in a large prospective cohort from the United States. Cancer Epidemiol Biomarkers Prev. 2009;18(12):3362-7.

Nomura AM, Wilkens LR, Henderson BE, Epplein M, Kolonel LN. The association of cigarette smoking with gastric cancer: the multiethnic cohort study. Cancer Causes Control. 2012;23(1):51-8.

Darré T, Sonhaye L, Tchaou M, Kanassoua K, Amadou A, Bagny A, et al. Histo-Epidemiological Profile of Digestive Cancers in Togo Journal of Cancer Research Updates. 2015;4:108-11.

Wands J. Hepatocellular carcinoma and sex. N Engl J Med. 2007;357(19):1974-6.

Pourhoseingholi MA, Vahedi M, Baghestani AR. Burden of gastrointestinal cancer in Asia; an overview. Gastroenterol Hepatol Bed Bench. 2015;8(1):19-27.

Yu MW, Chang HC, Chang SC, Liaw YF, Lin SM, Liu CJ, et al. Role of reproductive factors in hepatocellular carcinoma: Impact on hepatitis B- and C-related risk. Hepatology. 2003;38(6):1393-400.

Chbani L, Hafid I, Berraho M, Nejjari C, Amarti A. Digestive cancers in Morocco: Fez-Boulemane region. Pan Afr Med J. 2012;13:46.

Ramanampamonjy RM, Randria MJ, Razafimahefa SH, Ratsimandisa R, Rajaonarivelo P, Rajaona HR. Seroprevalence of infection due to Helicobacter pylori in a sample of Malagasy population. Bull Soc Pathol Exot. 2007;100 (1):57-60.

Coulibaly A, Sermé AK, Godonou H, Somda KS, Cissé K, Romond S, et al. Peptic Ulcer Disease in CHUYO. Open J Gastroenterol. 2016 Nov 9;6(11):353.

Torre LA, Bray F, Siegel RL, Ferlay J, Lortet-Tieulent J, Jemal A. Global cancer statistics, 2012. CA Cancer J Clin. 2015;65(2):87-108.

Ladep NG, Lesi OA, Mark P, Lemoine M, Onyekwere C, Afihene M, et al. Problem of hepatocellular carcinoma in West Africa. World J Hepatol. 2014 Nov 27;6(11):783.

Migliani R, Rousset D, Rakoto-Andrianarivelo M, Rabarijaona L, Ratsitorahina M, Rajaonarivony V, et al. Infection with the hepatitis B virus: a public health problem in Madagascar. Archives of the Pasteur Institute of Madagascar. 2000;66(1):50-4.

Ministry of public health Madagascar. Country Planning Cycle Database. Programme élargi de vaccination. 2012-2016. Available at: http://www.nationalplanningcycles.org/sites/default/files/country_docs/Madagascar/ppac_2012-_2016.pdf. Accessed 20 June 2018.

Downloads

Published

2019-09-25

How to Cite

Ranaivomanana, M., Rafaralahivoavy, T., Razafimahefa, J., Rakotovao, A. M., Rakotoarivelo, R. A., Razafimahefa, H. S., & Rafaramino, F. (2019). Epidemiology of gastrointestinal cancers in the hospital of Tambohobe Fianarantsoa, Madagascar. International Journal of Research in Medical Sciences, 7(10), 3619–3621. https://doi.org/10.18203/2320-6012.ijrms20194289

Issue

Section

Original Research Articles