DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20195912

Correlation of fine needle aspiration cytology and histopathology in the diagnosis of salivary gland lesions in a tertiary care hospital in the Southern part of Assam: a 2 year observational study

Musfika Tabassum, Monoj Kumar Deka, Nitu Mani Khakhlari

Abstract


Background: Fine Needle Aspiration Cytology (FNAC) of the salivary gland is one of the most challenging in the field of cytopathology due to the wide spectrum of lesions. There is significant cytomorphologic diversity and overlap between many benign and malignant salivary gland tumours. Though FNAC is quite an effective tool for the diagnosis of salivary gland lesions, it has always been under scrutiny and histopathology continues to be the final method to establish a diagnosis.

Methods: A total of 80 patients who presented with clinical diagnosis of salivary gland mass at the Department of Pathology, SMCH, Assam from August 2017 to August 2019 were included in the study. FNAC was performed in all the cases and the cytological findings were correlated with that of the histopathological findings (wherever possible).

Results: The median age group of patients was in the range of 30-40 years (30%). 60 patients underwent surgical procedure and hence histopathological correlation could be done in these patients. Among the various diagnosis in FNAC, benign tumours constitute the majority with 36 cases (60%). The most commonly involved benign tumour was pleomorphic adenoma (27 cases). The overall sensitivity, specificity & diagnostic accuracy of FNAC were found to be 87.3%, 93.9% and 93.33% respectively.

Conclusions: FNAC is a safe, reliable, time saving, cost-effective, convenient and accurate method and should be considered as one of the pivotal investigations in the evaluation of salivary gland lesions.


Keywords


Fine needle aspiration cytology, Pleomorphic adenoma, Salivary gland lesions, Sensitivity, Specificity

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References


Chan MK, McGuire LJ. Cytodiagnosis of lesions presenting as salivary gland swellings: a report of seven cases. Diag Cytopathol. 1992;8(5):439-43.

Zurrida S, Alasio L, Pilotti S, Tradati N, Chiesa F, Bartoli C. Fine‐needle aspiration of parotid masses. Cancer. 1993 Oct 15;72(8):2306-11.

Mavec P, Eneroth CM, Franzen S, Moberger G, Zajicek J. Aspiration biopsy of salivary gland tumours: I. Correlation of cytologic reports from 652 aspiration biopsies with clinical and histologic findings. Acta oto-laryngologica. 1964;58(1-6):471-84.

Speight PM, Barret AW. Salivary gland tumours. Oral Dis. 2002:8(5):229-40.

Kakoty S, Baruah TD, Babu CG. FNAC and histopathological correlation of salivary gland lesions: an observational study. Int Surg J. 2017;4(7):2148-52.

Kumar PV, Sobhani SA, Monabati A, Talei AR, Shirazi B. Cytologic findings of a pleomorphic adenoma of the breast: a case report. Acta Cytologica. 2004;48(6):849-52.

Gao N, Li Y, Li LJ, Wen YM. Clinical analysis of head and neck cancer cases in south-west China 1953–2002. J Int Med Res. 2009;37(1):189-97.

Verma K, Kapila K. Role of fine needle aspiration cytology in diagnosis of pleomorphic adenomas. Cytopathol. 2002;13(2):121-7.

Senguptal S, Roy A, Mallick MC, Kundu B, Das SK, Das S. FNAC of salivary glands. Ind J Otolaryngol Head Neck Surg. 2002;54(3):184-8.

Panchal U, Shah I, Hansa G. A cytological and histological comparative study of salivary gland lesions at tertiary health care centre. International J Biomed Advance Res. 2015;6(06): 470-4.

Cajulis RS, Gokaslan ST, Yu GH, Frias-Hidvegi D. Fine needle aspiration biopsy of the salivary glands. A five-year experience with emphasis on diagnostic pitfalls. Acta Cytologica. 1997;41(5):1412-20.

Das DK, Petkar MA, Al-Mane NM, Sheikh ZA, Mallik MK, Anim JT. Role of fine needle aspiration cytology in the diagnosis of swellings in the salivary gland regions: a study of 712 cases. Med Principles Pract. 2004;13(2):95-106.

Jayaram G, Dashini M. Evaluation of fine needle aspiration cytology of salivary glands: an analysis of 141 cases. Malaysian J Pathol. 2001 Dec;23(2):93-100.

Stow N, Veivers D, Poole A. Fine-needle aspiration cytology in the management of salivary gland tumors: an Australian experience. Ear, Nose Throat J. 2004 Feb;83(2):128-31.

Lukas J, Duskova J. Fine-needle aspiration biopsy in the diagnostic of the tumors and non-neoplastic lesions of salivary glands. Bratislavske lekarske listy. 2006;107(1/2):12.