DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20195927

Psychopathology in patients with psoriasis: a cross-sectional clinical study

Kumari Padma, Sagar Subhash Nanaware, Aruna Yadihal, P. John Mathai

Abstract


Background: Psoriasis is associated with a variety of psychological problems including poor self-esteem, sexual dysfunction, anxiety and depressive disorder and suicidal ideation. There are reports that patients with psoriasis may have significant psychiatric morbidity. The objective of the study is to evaluate the frequency of psychiatric disorders, frequency and nature of psychiatric symptoms in patients with psoriasis.

Methods: 100 patients with psoriasis were evaluated and included for the study. Comprehensive Psychopathological Rating Scale (CPRS) is used for assessment of psychiatric symptoms and MINI Plus for assessing psychiatric disorders. Chi-square test was used to compare the proportions.

Results: Patients with psoriasis had high frequency of psychiatric morbidity and was found to be 42%.

Conclusions: Patients with psoriasis have more psychopathology and higher psychiatric morbidity which may further imply justifiable consultation liaison psychiatry in other speciality fields like Dermatology.


Keywords


Psoriasis, Psychiatric morbidity, Psychodermatosis, Psychopathology

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References


Palfreeman AC, McNamee KE, McCann FE. New developments in the management of psoriasis and psoriatic arthritis: a focus on apremilast. Drug Design, Develop Therapy. 2013;7:201.

Taner E, Coşar B, Burhanoğlu S, Çalıkoğlu E, Önder M, Arıkan Z. Depression and anxiety in patients with Behçet's disease compared with that in patients with psoriasis. Int J Dermatol. 2007;46(11):1118-24.

Blauvelt A. New concepts in the pathogenesis and treatment of psoriasis: key roles for IL-23, IL-17A and TGF-β1. Expert Rev Dermatol. 2007;2(1):69-78.

Moon HS, Mizara A, McBride SR. Psoriasis and psycho-dermatology. Dermatol Therap. 2013;3(2):117-30.

Martín B, Sánchez-Carazo JL, Pérez-Ferriols A, Laguna C, Oliver V, Alegre V. Clinical experience with etanercept in the treatment of psoriasis. Actas Dermo-Sifiliográficas. 2008;99(7):540-5.

Sarkar S, Sarkar A, Saha R, Sarkar T. Psoriasis and psychiatric morbidity: a profile from a tertiary care centre of Eastern India. J Family Med Primary Care. 2014;3(1):29.

Griffiths CE, Barker RD. Psoriasis. In: Rook-W. Wilkinsum Ebling. Textbook of dermatology, Last ed. Blackwell Science. 2004.

Arnold L. Dermatology. Textbook of Psychosomatic Medicine. Ed Leveson 1st ed. Washington DC. Am Psychiatr Publishing; 2005:630-1.

Behnam SM, Behnam SE, Koo JY. Smoking and psoriasis. Skinmed. 2005;4:174-6.

Gottlieb A, Korman NJ, Gordon KB, Feldman SR, Lebwohl M, Koo JY, et al. Guidelines of care for the management of psoriasis and psoriatic arthritis: Section 2. Psoriatic arthritis: overview and guidelines of care for treatment with an emphasis on the biologics. J Am Acad Dermatol. 2008;58(5):851-64.

Stern RS, Nijsten T, Feldman SR, Margolis DJ, Rolstad T. Psoriasis is common, carries a substantial burden even when not extensive, and is associated with widespread treatment dissatisfaction. In J Invest Dermatol Symposium Proceed 2004;9:136-9.

Fortune DG, Richards HL, Kirby B, McElhone K, Markham T, Rogers S, et al. Psychological distress impairs clearance of psoriasis in patients treated with photochemotherapy. Archiv Dermatol. 2003;139(6):752-6.

Biljan D, Laufer D, Filaković P, Šitum M, Brataljenović T. Psoriasis, mental disorders and stress. Colleg Antropol. 2009;33(3):889-92.

Kumar S, Kachhawha D, Koolwal GD, Gehlot S, Awasthi A. Psychiatric morbidity in psoriasis patients: a pilot study. Ind J Dermatol Venereol Leprol. 2011;77(5):625.

Bharath S, Shamasundar C, Raghuram R, Subbakrishna DK. Psychiatric morbidity in leprosy and psoriasis--a comparative study. Ind J leprosy. 1997;69(4):341-6.

Golpour M, Hosseini SH, Khademloo M, Ghasemi M, Ebadi A, Koohkan F, et al. Depression and anxiety disorders among patients with psoriasis: A hospital-based case-control study. Dermatol Res Pract. 2012.

O'Leary CJ, Creamer D, Higgins E, Weinman J. Perceived stress, stress attributions and psychological distress in psoriasis. J Psych Res. 2004;57(5):465-71.

Hunter HJ, Griffiths CE, Kleyn CE. Does psychosocial stress play a role in the exacerbation of psoriasis? Br J Dermatol. 2013;169:965-74.

Schmitt JM, Ford DE. Role of depression in quality of life for patients with psoriasis. Dermatol. 2007;215(1):17-27.

Esposito M, Saraceno R, Giunta A, Maccarone M, Chimenti S. An Italian study on psoriasis and depression. Dermatol. 2006;212(2):123-7.

Tyring S, Gottlieb A, Papp K, Gordon K, Leonardi C, Wang A, et al. Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial. Lancet. 2006;367(9504):29-35.

Gowda S, Goldblum OM, McCall WV, Feldman SR. Factors affecting sleep quality in patients with psoriasis. J Am Acad Dermatol. 2010;63:114-23.

Basavaraj KH, Navya MA, Rashmi R. Stress and quality of life in psoriasis: an update. Int J Dermatol. 2011;50(7):783-92.