DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20200275

Evaluate the adequacy of disclosure as a solution to the problem of conflict of interest in medical research

Alanazi Mansour Moklif, Alanazi Mohammed Ratoubi

Abstract


A potential risk of conflict of interest currently exists in research.  The financial considerations play a greater role in the decisions that are necessary in the process of research. Traditional pharmaceutical companies began to invest, not just in the commercial development of biomedical discoveries for the marketplace, but in the research centres that could deliver the discoveries.  Cooperation and interdependence between industry and research institutions is not inherently wrong, but these unions must be regulated and managed through regulatory mechanisms. When a financial relationship is been disclosed, it would be closely evaluated in order to determine the risk of an undue influence leading to bias, or loss of scientific objectivity. To sum up, a conflict of interest is a potential, but not a certain occurrence. Banning funding for university research by industry is unrealistic.  The only effective way to proceed is to implement oversight and regulation that makes both industry funding entities and researchers aware that their activities will be monitored for the benefit of public safety as the more valued concern.


Keywords


Bias, Conflict of interest, Disclosure, Regulations, Research

Full Text:

PDF

References


Emanuel E, Thompson D. The Concept of Conflicts of Interest. The Oxford Textbook of Clinical Research Ethics. New York: Oxford University Press; 2008:758-766.

Thompson D. Understanding financial conflicts of interest. N Engl J Med. 1993;329(8):573-6.

Okike K, Kocher MS, Mehlman CT, Bhandari M. Conflict of Interest in Orthopaedic Research: An Association Between Findings and Funding in Scientific Presentations. J Bone Joint Surg Am. 2007;89(3):608-13.

Elliott KC. Scientific Judgment and the Limits of Conflict-of-Interest Policies. J Clin Res Best Pract. 2008;4(5):1-19.

Lo B. The future of conflicts of interest: A call for professional standards. J Law Med Ethics. 2012;40(3):441-51.

Stelfox H, Chua G, O’Rourke K, Detsky A. Conflict of interest in the debate over calcium-channel antagonists. N Eng J Med. 1998;338:101-6.

Shamoo AE, Resnik DB. Responsible conduct of research. Oxford University Press; 2009;3:213-5.

Foster RS. Conflicts of interest: Recognition, disclosure and management. Am Coll Surg. 2003;196(4):505-17.

Schafer A. Biomedical conflicts of interest:a defence of the sequestration thesis- learning from the cases of Nancy Olivieri and David Healy. J Med Ethics. 2004;30:8-24.

Lo B, Field MJ. Conflict of interest in medical research, education, and practice. Washington, DC: National Academy of Science Press; 2009.

Hampson LA, Bekelman JE, Gross CP. Empirical data on conflicts of interest. 2011;2:767-79.