DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20200776

Levels of serum lithium in manic depressive patients with mild persistent bronchial asthma

Subhramay Chatterjee, Sandip Chakraborti

Abstract


Background: Lithium, widely used in manic depressive (MD) patients, might protect the airways against constrictor stimuli in bronchial asthma (BA), through its effects on cell signal transduction and ion transport pathways.

Methods: Serum lithium levels were studied in MD patients with better controlled mild persistent BA (group A) and MD patients with not so well controlled BA (group B).

Results: Serum lithium levels were highly significantly more in group A compared to lithium levels in group B.

Conclusions: Lithium may inhibit the contractile response of airway smooth muscle and can be used in treatment / monitoring of BA.


Keywords


Bronchial asthma, Lithium, Manic depressive

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References


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