DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20201949

Antenatal diagnosis of omphalocele and spinal dysraphism: a possible OEIS complex

Dolly Khanna, Karandeep S. Bhatti

Abstract


OEIS complex, which comprises of omphalocele, exstrophy bladder, imperforate anus and spinal dysraphism, is a rare disorder. The prognosis depends upon the severity of the structural defects. Survival depends on the extension of the cloacal exstrophy and the neural tube defect. The antenatal diagnosis in early pregnancy is very tough, and a high level of suspicion should be kept for the possibility of its existence, even only if omphalocele and spinal dysraphism are seen on a prenatal sonography. Authors present the case of a 33-year-old, G1P0 female, who on her prenatal routine sonography scan, was found to have a fetus with omphalocele and spinal dysraphism. Despite the repeated attempts to follow her up, she refused and hence the possibility of the presence of other associated malformations could not be ascertained. Considering the difficulty of antenatal diagnosis of OEIS complex and its associated mortality, the objective of this case report is to discuss the vital sonographic findings of OEIS, along with its etiology and prognosis, which can aid in its early detection and subsequently help parents to make a decision regarding the continuation of pregnancy.


Keywords


Antenatal, OEIS complex, Omphalocele, Spinal dysraphism, Ultrasonography

Full Text:

PDF

References


Aneja K. A rare case of OEIS complex –newer approach to diagnosis of exstrophy bladder by colordoppler and its differentiation from simple omphalocele. Indian J Radiol Imaging. 2017;27(4):436-4.

Ben-Neriah Z, Withers S, Thomas M, Toi A, Chong K, Pai A, et al. OEIS complex: prenatal ultrasound and autopsy findings. Ultrasound Obstet Gynecol. 2007 Feb;29(2):170-7.

Omim.org. OMIM Entry - 258040 - OEIS Complex. Available at: https://www.omim.org/entry/258040 Accessed 27 February 2020.

Anon. OEIS Complex: A Rare Case Report. Available at: https://www.researchgate.net/publication/274350228_OEIS_COMPLEX_A_RARE_CASE_REPORT Accessed 27 February 2020.

Morales GM, Bustamante KF. Rojas IM. OEIS Complex, A Case Report. Available at: http://criticalcare.imedpub.com/oeis-complex-a-case-report.php?aid=8135 Accessed 28 February. 2020.

Weerakkody, Y. (2020). OEIS complex | Radiology Reference Article | Radiopaedia.org. [online] Radiopaedia.org. Available at: https://radiopaedia.org/articles/oeis-complex Accessed 27 February 2020.

Journals.sagepub.com. OEIS Complex A Case Report. Available at: https://journals.sagepub.com/doi/pdf/10.1177/8756479306297095 Accessed 28 February. 2020.

Deepblue.lib.umich.edu. Comprehensive Genetic Analysis of OEIS Complex Reveals No Evidence for a Recurrent Microdeletion or Duplication. [online] Available at: https://deepblue.lib.umich.edu/bitstream/handle/2027.42/83173/33757_ftp.pdf?sequence=1 Accessed 28 February 2020.

Sonoworld.com. OEIS complex. Available at: https://sonoworld.com/TheFetus/page.aspx?id=1765 Accessed 28 February 2020.