Demographic and clinical profile of vernal keratoconjunctivitis and testing of health related quality of life in a tertiary hospital in South India

Steffy Johnson, Justin Ignasious


Background: Patient with vernal keratoconjunctivitis faces significant morbidity, which affects quality of life or; moreover, it can lead to vision threatening, corneal complication in severe cases and chronic cases coupled with potential iatrogenic side effects. Aim of this study to assess the demography, clinical features and quality of life of patients with vernal keratoconjunctivitis in a centre in South India.

Methods: General objective is to access the health related-quality of life and demographic study of VKC patients in a tertiary eye care hospital in south India. KINDL questionnaire with 30 questions is used for 30 paediatric patients. Percentage analysis for clinical assessment and interpretation method for questionnaire was used as statistical method.

Results: In clinical assessment papillary reaction (96.66%), giant papillae (83.34%), Horner Trantas dots (20%), shield ulcer (13.35%), corneal erosions (43.33%), conjunctival congestion (76.68%). In case of vision 36.66% had normal vision, 56.67% had mild vision loss, 6.68% with moderate vision loss.

Conclusions: VKC affects the health related quality of life of the patients significantly. The management of VKC should consider this aspect of health related quality of life, in addition to clinical parameters. From the assessment of KINDL questionnaire 30 samples 18 patients had high and 12 patients had average quality of life.


Giant papillae, Horner Trantas dots, KINDL, Papillary, Shield ulcer, Vernal keratoconjunctivitis

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Bonini S CMASLA. Vernal keratoconjunctivitis. Eye. 2004 April;18(4)543-55.

Jack J, Kanski BB. Conjunctiva, Allergic conjunctivitis, Vernal keratoconjunctivitis in clinical ophthalmology a systemic approach. In: Jack J Kanski BB, eds. 8th ed. London: Elsevier-saunders; 2012: 145-150.

Leonardi A, Lazzarini D, Motterle L, Bortolotti M, Deligianni V, Curnow SJ, Bonini S, Fregona IA. Vernal keratoconjunctivitis-like disease in adults. Am J Ophthalmol. 2013 May 1;155(5):796-803.

Sacchetti M, Lambiase A, Mantelli F, Deligianni V, Leonardi A, Bonini S. Tailored approach to the treatment of vernal keratoconjunctivitis. Ophthalmology. 2010 Jul 1;117(7):1294-9.

Saboo US, Jain M, Reddy JC, Sangwan VS. Demographic and clinical profile of vernal keratoconjunctivitis at a tertiary eye care center in India. Ind J Ophthalmol. 2013 Sep;61(9):486-9.

Tabbara KF. Ocular complications of vernal keratoconjunctivitis. Canad J Ophthalmol. 1999 Apr;34(2):88-92.

Rao IP, Sundar PS, Naik SK. Clinical And Demographic Profile of Vernal Keratoconjunctivitis At A Tertiary Eye Care Center in Andhra Pradesh. IOSR- J Dent Medi Sci. 2016;15:55-9.

Kawuma M. The clinical picture of vernal kerato-conjunctivitis in Uganda. Comm Eye Health. 2001;14(40):66-7.

Sacchetti M, Baiardini I, Lambiase A, Aronni S, Fassio O, Gramiccioni C, et al. Development and testing of the quality of life in children with vernal keratoconjunctivitis questionnaire. Am J Ophthalmol. 2007 Oct 1;144(4):557-63.

Malu KN. Vernal keratoconjunctivitis in Jos, North-Central Nigeria: A hospital-based study. Sahel Medi J. 2014 Apr 1;17(2):65-70.

Sofi RA, Mufti A. Vernal Keratoconjunctivitis in Kashmir: A temperate zone. Int Ophthalmol. 2016 Dec 1;36(6):875-9.