DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20204877

Comparison of blood glucose in obese and non-obese students in a medical college

Aparna Chaudhari, Shreya Gujarathi, Geeta Bhatia

Abstract


Background: Obesity has a negative effect on health, leading to reduced life expectancy and/or increased health problems. It is one of the underlying causes of non-communicable chronic diseases like type II diabetes, stroke etc. The study was aimed to compare blood glucose levels in obese and non-obese students in a medical college and to show that obese students are more prone to develop type II diabetes.

Methods: A total 20 obese subjects with age and sex matched 20 non-obese subjects were chosen. Their venous blood samples were collected after 12 hours of fasting and analysed for fasting blood sugar (FBS) and haemoglobin A1c (HbA1c).

Result: Results of the study showed that obese students have significant (p<0.001) high blood glucose and HbA1c levels as compared to non-obese students.

Conclusion: The obese students are prone to develop type II diabetes due to changes in body metabolism as a result of change in fat distribution.


Keywords


Obese, Non- obese, Blood glucose, HbA1c

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References


Sisodia RK, Chouhan M. The study of correlation between Body Mass Index and glycemic control-HbA1c in Diabetes type 2 patients. Int J Adv Med. 2019;6:1788-91.

WHO. Obesity and overweight Fact sheet N 311. 2015. Available at: www.who.int>media>gsts_obesity. Assessed on 2nd February 2016

Haslam DW, James WP. Obesity. Lancet. 2005;366(9492):1197-209.

Shabana S, Ramya K, Sasisekhar T.V.D, Santosh Kumar A. HbA1c as an Index of Glycemic Status in Obese Type 2 Diabetics. Int. j. clin. biomed. res. 2017;3(3): 34-39.

Misra A, Chowbey P, Makkar BM, Vikram NK, Wasir JS, Chadha D. Consensus Statement for Diagnosis of Obesity, Abdominal Obesity and the Metabolic Syndrome for Asian Indians and Recommendations for Physical Activity, Medical and Surgical Management. J Asso Physicians India. 2009;57:163-70.

Luppino FS, de Wit LM, Bouvy PF, Stijnen T, Cuijpers P, Penninx BW et al. Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies. Arch General Psychiatry. 2010;67(3):220-9.

Christy AL, Manjrekar PA, Babu RP, Hegde A. Influence of Iron deficiency Anemia on HbA1c levels in Diabetic Individuals with controlled plasma glucose levels. Iranian biomed j. 2014;18(2):88-93.

Woo YC, Cheung BM, Yeung CY, Lee CH, Hui EY, Fong CH et al. Cardiometabolic risk profile of participants with prediabetes diagnosed by HbA1c criteria in an urban Hong Kong Chinese population over 40 years of age. Diabetic Med. 2015;32(9):1207-11.

Flier JS, Maratos-Flier E. Pathobiology of obesity. In: Anthony S. Fauci, editor. Harrison’s principals of internal medicine. 20th ed. New Delhi: Mc Graw Hill Education, 2018:2837-42.

Innocent O, ThankGod OO, Sandra EO Josiah IE. Correlation between body mass index and blood glucose levels among some Nigerian undergraduates. HOAJ Biol. 2013;2:4.

Kumar S, Mahabalaraju KD, Anuroopa MS. Prevalence of obesity and its influencing factor among affluent school children of Devanagere city. Indian J Community Med. 2007;32:15-7.

Srinivasan K, Vaz M, Sucharita S. A study of stress and autonomic nervous function in first year undergraduate medical students. Indian J Physiol Pharmacol, 2006;50:257-64.

Vasudevan DM. Ch. 11 in textbook of Biochemistry, 8th ed. JAYPEE the health sciences publisher. 2016;168.

Fernandez K, Singru SA, Kshirsagar M, Pathan Y. Study regarding overweight/obesity among medical students of teaching hospital in Pune, India. Med J DY Patil Univ. 2014:7;279-83.

Tietz NW, Burtis CA, Ashwood ER, Bruns DE. Spectrophotometry. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics, 4th ed. Elsevier. 2006;64-5.

Thomas L. Clinical laboratory Diagnostics, 1st ed, Frankfury: TH books Verlagsgesllschaft. 1998;142-8.

Sheth J, Shah A, Sheth F, Trivedi S, Nabar N, Shah N et al. The association of dyslipidemia and obesity with glycated haemoglobin. Clinical Diabetes and Endocrinology. Clin Diabetes Endocrinol. 2015:1-6.

Bays HE, Chapman RH, Grandy S; SHIELD Investigators' Group. The relationship of body mass index to diabetes mellitus, hypertension and dyslipidaemia: comparison of data from two national surveys. Int J Clin Pract. 2007;61(5):737-47.

Shah A, Parthasarathi D, Sarkar D, Saha CG. A comparative study of body mass index (BMI) in diabetic and non-diabetic individuals in Nepalese population. Kathmandu Univ Med J. 2006;4(1):4-10.

Shi YH, Zhao DN, Zhao JL, You L, Liu H, Mei Sun et al. Search articles by 'Mei Sun' Sun M. Characteristics of glucose metabolism in non-obese and obese women with polycystic ovarian syndrome. Zhonghua Fu Chan Ke Za Zhi. 2010;45(8):575-7.

Tomić M, Tamara P, Pavlic-Renar I, Metelko Ž. Obesity-risk factor for microvascuar and neuropatic complication in diabetes? Diabetologia Croatica. 2003;32(3):73-7

Babikr WG, Alshahrani AS, Hamid HG, Abdelraheem AH, Shalayel MH. The correlation of HbA1c with body mass index and HDL-cholesterol in type 2 diabetic patients. Biomed Res. 2016;27(4):1280-3.