The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients

Authors

  • Ade Ramadhani Department of Ear Nose Throat- Head and Neck Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia
  • Anna M. K. Dewi Department of Ear Nose Throat- Head and Neck Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia
  • Kanthi Yunika Department of Ear Nose Throat- Head and Neck Surgery, Faculty of Medicine, Diponegoro University, Semarang, Indonesia
  • Rery Budiarti Department of Ear Nose Throat- Head and Neck Surgery, Dr. Kariadi Central General Hospital, Semarang, Indonesia
  • Dian A. Ruspita Department of Ear Nose Throat- Head and Neck Surgery, Dr. Kariadi Central General Hospital, Semarang, Indonesia
  • Farokah . Department of Ear Nose Throat- Head and Neck Surgery, Dr. Kariadi Central General Hospital, Semarang, Indonesia
  • Muyassaroh . Department of Ear Nose Throat- Head and Neck Surgery, Dr. Kariadi Central General Hospital, Semarang, Indonesia

DOI:

https://doi.org/10.18203/2320-6012.ijrms20205299

Keywords:

LPR, Psychiatric symptoms, Quality of life, Risk factors

Abstract

Background: Risk factors for laryngopharyngeal reflux (LPR), such as age, gender, BMI, smoking history and dietary habit affect the severity of LPR. These risk factors have a clinical impact on both social and emotional aspects, which can reduce the quality of life. Thus led the researchers to analyse association between these risk factors with psychiatric symptoms and quality of life for LPR sufferers.

Methods: Analytical descriptive research with cross-sectional approach to LPR patients in ENT clinic RSUP Dr. Kariadi Semarang. Sixty six samples aged 18-60 years and met the criteria of the researcher were measured using the DASS 21 questionnaire and the RQS questionnaire. Statistical analysis used the chi-square test.

Results: Obtained 66 subjects with a mean age of 45.1 years, there were more women than men (75.8%). Analysis of risk factors associated with depression found gender (p=1.000), age (p=1.000), duration of symptoms (p=1.000), BMI (p=0.132), smoking (p=0.452), and diet (p=1.000). Analysis of risk factors with anxiety obtained gender (p=0.340), age (p=0.743), duration of symptoms (p=0.085), BMI (p=0.322), smoking history (p=1.000), and diet (p=1.000). Analysis of risk factors with stress obtained gender (p=0.798), age (p=0.088), duration of symptoms (p=0.324), BMI (p=0.276), smoking history (p=0.606) and diet (p=0.538). Analysis of the gender association related to the quality of life LPR patients (p=0.032).

Conclusions: Duration of symptoms, age, BMI, smoking history and diet were not associated with psychiatric symptoms and quality of life in LPR sufferers. Gender is not associated with psychiatric symptoms but is related to quality of life.

References

Lechien JR, Saussez S, Karkos PD. Laryngopharyngeal reflux disease. Curr Opin OtolaryngolHead Neck Surg. 2018;1(26):392-402.

Nunes HS, Pinto JA, Zavanela AR, Cavallini AF, Freitas GS, Garcia FE. Comparison between the reflux finding score and the reflux symptom index in the practice of otorhinolaryngology. Int Arch Otorhinolaryngol. 2016;20:218-21.

Akst LM, Haque OJ, Clarke JO, Hillel AT, Best SR, Altman KW. The changing impact of gastroesophageal reflux disease in clinical practice. Ann Otol Rhinol Laryngol. 2017;126:229-35.

Chen XM, Li Y, Guo WL, Wang WT, Lu M. Prevalence of laryngopharyngeal reflux disease in Fuzhou region of China. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016;51:909-13.

Blumin JH. Laryngopharyngeal Reflux. In: Johnson J, edr. Bailey’s Head and Neck Surgery Otolaryngology. 5th edn. Baltimore: Lippincott Williams and Wilkins; 2015:958-977.

Karakaya NE, Akbulut S, Altintas H, Demir MG, Demir N, Berk D. The reflux finding score: reliability and correlation to the reflux symptom index. J Acad Res Med. 2015;5(2):68-74.

Spantideas N, Drosou E, Bougea A, Assimakopoulos D. Laryngopharyngeal reflux disease in the Greek general population, prevalence and risk factors. BMC Ear Nose Throat Disord. 2015;15(1):7.

Lee SW, Lee TY, Lien HC, Peng YC, Yeh HJ, Chang CS. Correlation between symptom severity and health-related life quality of a population with gastroesophageal reflux disease. Gastroenterol Res. 2017;10(2):78-83.

Francis DO, Patel DA, Sharda R, Hovis K, Sathe N, Penson DF, et al. Patient-reported outcome measures related to laryngopharyngeal reflux: a systematic review of instrument development and validation. Otolaryngol Head Neck Surg. 2016;155(6):923-35.

Newberry C, Lynch K. The role of diet in the development and management of gastroesophageal reflux disease: why we feel the burn. J Thorac Dis. 2019;11(12):S1594-601.

Guan XL, Wang W. Quality of life scales for patients with gastroesophageal reflux disease: a literature review. Int J Nurs Sci. 2015;2:110-4.

Li CF, Zhang LH, Wang WL, Cao J, Wang YG, Zhao YX. The prevalence and relationship between laryngopharyngeal reflux disease, anxiety and depression in otolaryngology outpatients. Chinese J Otorhinolaryngol Head Neck Surg. 2020;55(3)241-8.

Yang XJ, Jiang HM, Hou XH, Song J. Anxiety and depression in patient with gastroesophageal reflux disease and their effect in quality life. World J Gastroenterol. 2015;21(14):4302-9.

Joo YH. Globus pharyngeus: the psychiatric perspective. J Korean Soc Laryngol Phoniatr Logoped. 2016;27(2):84-6.

Mesallam TA, Shoeib RM, Farahat M, Kaddah FEA, Malki KH. Studying the psychological profile of patients with laryngopharyngeal reflux. Folia Phoniatrica et Logopaedica. 2015;67(2):51-6.

Joo YH, Song YS, Pae CU. Relationship between depression and laryngopharyngeal reflux. Psychiatr Investig. 2017;14(2):227-9.

Siregar GA, Halim S, Sitepu RR. Dyspepsia and depression, anxiety, stress scales score. Indonesian J Gastroenterohepatol Digest Endosc. 2016;17(1):28-31.

Lee JS, Lee YC, Kim SW, Kwon KH, Eun YG. Changes in the quality life of patients with laryngopharyngeal reflux after treatment. J Voice. 2014;28(4):487-91.

Gong EJ, Choi KD, Jung HK, Youn YH, Min BH, Song KH, et al. Quality of life, patient satisfaction, and disease burden in patients with gastroesophageal reflux disease with or without laryngopharyngeal reflux symptoms. J Gastroenterol Hepatol. 2017;32(7):1336-40.

Downloads

Published

2020-11-27

How to Cite

Ramadhani, A., Dewi, A. M. K., Yunika, K., Budiarti, R., Ruspita, D. A., ., F., & ., M. (2020). The association of risk factors with psychiatric symptoms and quality of life in laryngopharyngeal reflux disease patients. International Journal of Research in Medical Sciences, 8(12), 4251–4257. https://doi.org/10.18203/2320-6012.ijrms20205299

Issue

Section

Original Research Articles