DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20204923

Very late (>5 years) thrombus formation on an atrial septal defect device: a case report

Sudheer Venkata Bolinera, Srinivas Soma, Sanivarapu Srinivasa Reddy, Vijaya Pamidimukkala, Michael Naronha, Deepti Gali, Vikas Somnath Khamkar, Muralibaburao Rachaputi, Anurag Polavarapu, Naren Polavarapu, Sirichandana Gangasani, Sravanthi Byrapaneni, Meghana Chilukuri, Raghava Sarma Polavarapu

Abstract


Though percutaneous transcatheter atrial septal defect closure with newer generation occluder devices is a standard treatment at present, these devices have significant long-term risks (>1 year) associated with such as thrombus formation. Here, we present a case of 28 year-old patient presented with few symptoms and had a history of ASD device closure using amplatzer septal occluder device five years back. The patient was found to have a large thrombus (30×33 mm) attached to the device which was managed using anticoagulants and patients was advised for regular echocardiographic follow-up.


Keywords


Atrial septal defect, Percutaneous device closure, Thrombus, Late complications

Full Text:

PDF

References


Bissessor N. Current perspectives in percutaneous atrial septal defect closure devices. Med Devices. 2015;8:297.

Belgrave K, Cardozo S. Thrombus formation on amplatzer septal occluder device: pinning down the cause. Case Rep Cardiol. 2014;2014(9):457850.

Zaidi AN, Cheatham JP, Galantowicz M, Astor T, Kovalchin JP. Late thrombus formation on the helex septal occluder after double-lung transplant. J Heart Lung Transplant. 2010;29:814-6.

Abaci A, Unlu S, Alsancak Y, Kaya U, Sezenoz B. Short and long term complications of device closure of atrial septal defect and patent foramen ovale: meta‐analysis of 28,142 patients from 203 studies. Catheter Cardiovasc Interv. 2013;82:1123-38.

Ruge H, Wildhirt S, Libera P, Vogt M, Holper K, Lange R. Left atrial thrombus on atrial septal defect closure device as a source of cerebral emboli 3 years after implantation. Circulation. 2005;112:e130-1.

Olabiyi OO, Morales DL, Franklin WJ. De novo thrombus on an atrial septal defect device 3 years after its implantation. Pediatr cardiol. 2013;34:1269-71.

Uysal F, Bostan ÖM, Sığnak IŞ, Güneş M, Çil E. Huge thrombus formation 1 year after percutaneous closure of an atrial septal defect with an amplatzer septal occluder. Anatol J Cardiol. 2016;16:63.

Giraldo-Gonzalez GC, Olaya P, Domínguez A, Sanchez J, Vesga CE. Very Late Amplatzer Device Thrombosis and Stroke. Case. 2019;4(1):25-7.

Gaul C, Heckmann JG, Bremer J, et al. Thrombus attached to a Sideris septal occluder system 6 years later. 2004;129(3):87-90.

Misra S, Conte J, Resar J. Left atrial thrombus associated with interatrial septal occluder 5 years after implantation. Circulation: Cardiovasc Interv. 2015;8:e002856.

Krumsdorf U, Ostermayer S, Billinger K, Trepels T, Zadan E, Horvath K, Sievert H. Incidence and clinical course of thrombus formation on atrial septal defect and patient foramen ovale closure devices in 1,000 consecutive patients. J Am Coll Cardiol. 2004;43(2):302-9.

Wiktor DM, Carroll JD. ASD closure in structural heart disease. Curr Cardiol Rep 2018;20:37.