The duration of antiretrovirals administration and hearing impairment in HIV-infected patients

Authors

  • Bima Riantardo Hafni Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Dian Ayu Ruspita Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Muchlis Achsan Udji Sofro Department of Internal Medicine, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Riece Hariyati Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Zulfikar Naftali Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Willy Yusmawan Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Anna Mailasari K. D. Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia
  • Muyassaroh . Department of Otolaringology-Head and Neck Surgery, Diponegoro University Faculty of Medicine, Dr. Kariadi Hospital, Semarang, Indonesia

DOI:

https://doi.org/10.18203/2320-6012.ijrms20210406

Keywords:

Human immunodeficiency virus, Antiretroviral, Hearing impairment

Abstract

Background: Antiretrovirals (ARV) treatment in HIV has a role in preventing HIV transmission, because ARV drugs have a mechanism of action to prevent viral replication which gradually reduces the amount of virus in the blood. Nucleoside analogue reverse transcriptase inhibitors (NRTIs) are a type of ARV that has side effects of hearing impairment. This research was purposed to determine the relationship between the duration of ARV administration with hearing impairment HIV-infected patients.

Methods: We used a cross-sectional design in HIV patients aged 19-59 years who were undergoing ARV treatment at Dr. Kariadi Semarang. We identified 91 patients whose complaints of hearing impairment (tinnitus and/or hearing loss) obtained from the history. We analyzed the data with the chi-square test, fisher's exact and yate correlation.

Results: There were 91 respondents who received ARVs. Male 62 people (68.1%) female 29 people (31.9%), the youngest was 19 years old, the oldest was 52 years old, mean age was 34.8 years+ 8,04. The duration of ARV administration was not associated with tinnitus (p=0.385), hearing loss (p=0.344), and hearing impairment (p=0.454).

Conclusions: The duration of ARV administration was not associated with tinitus, hearing loss, hearing impairment.

References

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Published

2021-01-29

How to Cite

Hafni, B. R., Ruspita, D. A., Sofro, M. A. U., Hariyati, R., Naftali, Z., Yusmawan, W., K. D., A. M., & ., M. (2021). The duration of antiretrovirals administration and hearing impairment in HIV-infected patients. International Journal of Research in Medical Sciences, 9(2), 330–333. https://doi.org/10.18203/2320-6012.ijrms20210406

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Section

Original Research Articles