Exotic associations and presentations of an age old disease: spectrum of tuberculosis in a developing country

Authors

  • Sujata Jetley Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi
  • Zeeba S. Jairajpuri Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi
  • Mukta Pujani Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi
  • Sabina Khan Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi

DOI:

https://doi.org/10.18203/2320-6012.ijrms20161818

Keywords:

Tuberculosis, Associations, Presentation, Developing country

Abstract

Background:To create an awareness of the associations of tuberculosis with various other infections and its atypical clinical manifestations is important especially in regions where tuberculosis continues to be a major public health problem.

Methods: This was an observational study of tubercular cases received in the Department of Pathology during the period January 2014 to January 2015.

Results: A case series of exotic associations of tuberculosis, along with two cases at unusual sites, not suspected clinically, subsequently diagnosed by pathological examination and ancillary techniques.

Conclusions: Tuberculosis continues to be a major cause of morbidity and mortality especially in the developing world. This series of cases goes to demonstrate the seemingly endless forms and presentations of this age-old disease and the importance of timely diagnosis and specific treatment.

References

Meyer JA. Tuberculosis, the adirondacks, and coming of age for thoracic surgery. Ann Thorac Surg. 1991;52:881-5.

Carter KC, ed. Essays of robert koch: contributions in medical studies. Westport: Greenwood Press. 1987:9-25.

AIDS Control and Prevention (AIDSCAP) Project of Family Health Internal. The Francois-Xavier Bagnoud Center for Public Health and Human Rights Of the Harvard School of Public Health, UNAIDS. The Status and Trends of the Global HIV/AIDS Pandemic. Final Report. 1996:5-6.

Raviglione MC, Narain JP, Kochi A. HIV-associated tuberculosis in developing countries: clinical features, diagnosis, and treatment. Bull World Health Organ. 1992;70:515-26.

Sievers ML. The Second Great Imitator-Tuberculosis. JAMA. 1961;176(9):809-10.

Bahadur S, Pujani M, Jetley S, Hassan MJ, Khetrapal S, Husain M. Coexistent axillary hydatid disease and tuberculosis: case report of an extremely rare occurrence. J Cytol. 2014;31:32-5.

World Health Organization: global tuberculosis control: epidemiology, strategy, financing. WHO report 2010.

Sharma SK, Mohan A. Extra pulmonary tuberculosis. Ind J Med Res. 2004;120(4):316-53.

Haldar S, Bose M, Chakrabarti P, Daginawala HF, Harinath BC, Kashyap RS et al., Improved laboratory diagnosis of tuberculosis: the Indian experience. Tuberculosis. 2011;91(5):414-26.

Chakravorty S, Sen MK, Tyagi JS. Diagnosis of extra pulmonary tuberculosis by smear, culture, and PCR using universal sample processing technology. J Clin Microbiol. 2005;43(9):4357-62.

Avcu S, Unal O, Kotan C, Ozturk M, Ozen O. Submandibular and thyroid gland involvement of hydatid cysts: a very rare association with percutaneous treatment. Diagn Interv Radiol. 2010;16:251-4.

Das DK, Bhambhani S, Pant CS. Ultrasound guided fine needle aspiration cytology: diagnosis of hydatid disease of the abdomen and thorax. Diagn Cytopatho. 1995;12:230-3.

Handa U, Bal A, Mohan H. Cytomorphology of hydatid disease. The Internet Journal of Tropical Medicine. 2004;2(1).

Iynen I, Sogut O, Guldur ME, Kose R, Kaya H, Bozkusa F. Primary hydatid cyst: an unusual cause of a mass in supraclavicular region of neck. J Clin Med Res. 2011;3:52-4.

Grace MS. Coinfection of two age old diseases. Indian J Community Med. 2011;36:228-30.

Relvich AL. The treatment of tuberculosis in leprosy patients. Lepr Rev. 1954;25:179-86.

Arora VK, Johri A. Reactivation of tuberculosis and leprosy in an HIV-positive case. Tuber Lung Dis. 1994;75(3):235-8.

Agarwal DK, Mehta R, Sharma AP, Sural S, Kumar A, Mehta B. Coinfection with leprosy and tuberculosis in a renal transplant patient. Nephrol Dial Transplant. 2000;15(10):1720-1.

Sreramareddy CT, Menezes RG, Kishore P. Concomittent age old infections of mankind: a case report. J Med Case Reports. 2007;5(1):43.

Prasad R, Verma SK, Singh R, Hosmane G. Concomittant pulmonary tuberculosis and leprosy with Type-II Lepra reaction in single patient. Lung India. 2010;27:19-23.

Ligthelm LJ, Nicol MP, Hoek HG, Jacobson R, van Helden PD, Marais BJ. Xpert MTB/RIF for rapid diagnosis of tuberculous lymphadenitis from fine-needle-aspiration biopsy specimens. J Clin Microbiol. 2011;49:3967-70.

Meyer EC, Scatliff JH, Lindskog GE. The relation of antecedent tuberculosis to bronchogenic carcinoma. A study of the tuberculin test, radiologic and pathologic evidences. J Thorac Cardiovasc Surg. 1959;38:384-97.

Falagas ME, Kouranos VD, Athanassa Z, Kopterides P. Tuberculosis and malignancy. QJM. 2010;103:461-87.

Chaturvedi P, Pai PS, Chaukar DA, Deshpande MS, Rangarajan V, Purandare N, et al. Extensive tubercular neck lymphadenopathy in a man with early-stage tongue cancer. Nat Clin Pract Oncol. 2007;4:726-8.

Landa LE, Kathju S, Nepomuceno-Perez MC, Gordon C, Sotereanos GC. Tuberculous granuloma and adenoid cystic carcinoma presenting as a single buccal space mass. J Craniofac Surg. 2002;13:533-7.

Bishara J, Calderon S, Okon E, Shevach I, Maimon S, Pitlik S. Coexisting extra pulmonary tuberculosis and malignancy. Am J Med. 1998;105:443-6.

Gal G, Kaplan I, Calderon S, Carlson ER. Large perimandibular swelling. J Oral Maxillofac Surg. 1997;55:1134-43.

Volker HU, Scheich M, Holler S, Ströbel P, Hagen R, Müller-Hermelink HK. Differential diagnosis of laryngeal spindle cell carcinoma and inflammatory myofibroblastic tumor-report of two cases with similar morphology. Diagnostic Pathology. 2007;2:1.

Katase N, Tamamura R, Gunduz M, Murakami J, Asaumi JH, Tsukamoto G, Sasaki A. A spindle cell carcinoma presenting with osseous metaplasia in the gingiva: a case report with immune histochemical analysis. Head and Face Medicine. 2008;4:1.

Marchetti G, Gori A, Catozzi L, Vago L, Nebuloni M, Cristina Rossi M. Evaluation of PCR in detection of Mycobacterium tuberculosis from formalin fixed paraffin embedded tissues: comparison of four amplification assays. J of Clin Microbiol. 1998;36(6):1512-17.

Cooper A. Illustrations of the diseases of the breast: Part 1. London: Longman, Rees Orme, Brown and Green; 1829:73.

Mukerjee P, George M, Maheshwari HB, Rao CP. Tuberculosis of the breast. J Indian Med Assoc. 1974;62:410-2.

Tewari M, Shukla H.S. Breast tuberculosis: Diagnosis, clinical features and management. Indian J Med Res. 2005;122:103-10.

Gupta V, Mohan H, Jain P, Singh S, Singla N. Tuberculous mastitis: a report of two cases in elderly females. Jpn J Infect Dis. 2006;59:279-80.

Khanna R, Prasanna GV, Gupta P, Kumar M, Khanna S, Khanna AK. Mammary tuberculosis: report on 52 cases. Postgrad Med J. 2002;78:422-4.

Kakkar S, Kapila K, Singh MK, Verma K. Tuberculosis of the breast. A cyto morphologic study. Acta Cytol. 2000;44:292-6.

Lamba H, Byrne M, Goldin R, Jenkins C. Tuberculosis of the cervix: case presentation and a review of the literature. Sex Transm Inf. 2002;78:63-6.

Chowdhury NN. Overview of tuberculosis of the female genital tract. J Indian Med Assoc. 1996;94:345-6,361.

Singh S, Gupta V, Modi S, Rana P, Duhan A, Sen R. Tuberculosis of uterine cervix: a report of two cases with variable clinical presentation. Tropical Doctor. 2010;40:125-6.

Singhal SR, Chaudhry P, Nanda S. Genital tuberculosis with predominant involvement of cervix: a case report. Clin Rev Opin. 2011;3:55-6.

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Published

2017-01-02

How to Cite

Jetley, S., Jairajpuri, Z. S., Pujani, M., & Khan, S. (2017). Exotic associations and presentations of an age old disease: spectrum of tuberculosis in a developing country. International Journal of Research in Medical Sciences, 4(6), 2379–2387. https://doi.org/10.18203/2320-6012.ijrms20161818

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Original Research Articles