DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20211362

Histopathological study of nasal masses, a one year retrospective study in a tertiary care centre of Assam

Nurul Alam, S. K. Abdullah Ahmed, Monoj K. Deka, Shah Alam Sheikh

Abstract


Background: Prolapsed lining of the nasal sinuses are defined as nasal polyp. Diseases of the nasal cavity include viral, bacterial and fungal infections, nasal cavity tumors (benign and malignant) as well as inflammations of the nasal mucosa. This study was undertaken to note the various histopathological patterns of nasal masses, their classification and relative distribution of various lesions with regard to age and sex in our setting.

Methods: The study is done for a period of 1 year (July 2018 to June 2019). In this study, 30 patients are selected who presented in our hospital with nasal masses and having multiple types of clinical presentations.

Results: Total 30 cases presented as nasal mass. Overall male to female ratio was 2.3:1. Nonneoplastic nasal masses formed the largest group of lesions; 24 cases (80%), followed by 6 cases (20%) of neoplastic nasal masses. Inflammatory polyp was the commonest non neoplastic lesion constituting 22 cases followed by rhinosporidiosis with 2 cases. Out of the 6 neoplastic nasal masses, 5 were benign and 1 was malignant. Out of the benign neoplastic masses, inverted papilloma constituted 3 cases and nasopharyngeal angiofibroma constituted 2 cases. Malignant neoplastic mass was embryonal rhabdomyosarcoma.

Conclusions: Nasal obstruction and rhinorrhea are the most common symptoms of presentation. Simple inflammatory nasal polyps are the most common histological pattern seen in our environment, and surgery is the best modality of treatment.


Keywords


Nasal mass, Histopathology, Nasal polyps

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References


Young B, Heath JW. In: Wheater’s functional Histology. A text and colour atlas. 4th Edition. Churchill Livingstone. 2000;222-5.

Maru AM, Patel UV, Shrivastav A, Lakum NR, Choksi TS, Agnihotri A S. Histopathological study of nasal masses in patients coming to a tertiary care hospital: A study of 70 cases. Med J DY Patil Univ. 2015;8:468-73.

Humayun AHM, Zahurul Huq AHM, Ahmed SMT. Clinicopathological study of sinonasal masses. Bangladesh J Otorhinolaryngol. 2010;16:15-22.

Dasgupta A, Ghosh RN, Mukherjee C. Nasal polypshistopathologic spectrum. Indian J Otolaryngol Head Neck Surg. 1997;49(1):32-7.

Eggston AA, Wolf D. Histopathology of Ear, Nose and Throat. 2nd Edition. Williams and Wilkins. 1947.

Garg D, Mathur K. Clinico-pathological study of space occupying lesions of nasal cavity, paranasal sinuses and nasopharynx. J Clin Diagn Res. 2014;8(11):42-8.

Parajuli S, Tuladhar A. Histomorphological spectrum of masses of the nasal cavity, paranasal sinuses and nasopharynx. J Pathol Nepal. 2013;3(5):351-5.

Zafar U. Khan, Afroz N. Clinicopathological study of non-neoplastic lesions of nasal cavity. Indian J Pathol Microbiol. 2008;51:26-9.

Panchonia A, Kulkarni CV, Singh R. Histological correlation of nasal mass: a five year retrospective and prospective study. Int J Res Med Sci. 2014;2:842-6.

Bandil S, Kumar H, Kumar H. Histopathological Study of Lesions of Nasal Cavity. Ann Int Med Dent Res. 2019;5(5):15-8.

Parmar NJ, Jethwani DP, Dhruva GA. Histopathological study of nasal lesions: 2 years study. Int J Res Med Sci. 2018;6:1217-23.

Kirtsreesakul V. Nasal polyps: The relationship to allergy, sinonasal infection and histopathological type. J Med Assoc Thai. 2004;87:277-82.

Makannavar JH, Chavan SS. Rhinosporidiosis—a clinicopathological study of 34 cases. Indian J Pathol Microbiol. 2001;44:17-21.

Tondon PL, Gulati J, Mehta N. Histological study of polypoidal lesions in the nasal cavity. Indian J Otolaryngol. 1971;13:3-11.

D’Angelo AJ, Marlowe A, Marlowe FI, McFarland M. Inverted papilloma of the nose and paranasal sinuses in children. Ear Nose Throat J. 1992;71:264-6.

Ringertz N. Pathology of malignant tumors arising in the nasal and paranasal cavities and maxilla. Acta Otolaryngol. 1938;27:31-42.

Wikivet. Spindle Cell Tumours. Available at: https://en.wikivet.net/Spindle_ Cell_Tumours. Accessed on 01 September 2018.

Koshy S, George M, Gupta A, Daniel RT. Extended osteoplastic maxillotomy for total excision of giant multicompartmental juvenile nasopharyngeal angiofibroma. Indian J Dent Res. 2008;19:366-9.

Gensler MB. Sinonasal and nasopharyngeal surgical pathology. In: Silverberg SG, editor. Silverberg’s Principles and Practice of Surgical Pathology and Cytopathology. 4th ed. Philadelphia: Churchill Livingstone Elsevier. 2006;793-811.