DOI: http://dx.doi.org/10.18203/2320-6012.ijrms20212523

Clinicopathological study of bacterial lesions in a tertiary care hospital

Sonti Sulochana, Jalavadi Rahul Siddartha

Abstract


Background: The incidence of bacterial lesions has been on the rise over the decades. In our study, we assessed and studied the spectrum of bacterial lesions retrospectively for one year and their clinicopathological correlation which was diagnosed on histopathological examination in a tertiary health care center.

Methods: The present study (retrospective) has been done to analyse the incidence of bacterial infections obtained in the histopathology laboratory and study its clinical correlation and significance. Clinical details of the cases were accessed from biopsy requisition forms and included tissues from various sites in the body. Special stains were done which included acid fast bacilli (AFB), Fite Farraco (FF) stain and gram stain for the identification of bacteria.

Results: A total of 318 cases including 288 H. pylori infections, granulomatous inflammation 18, Hansen disease 9 and 3 actinomycosis infections.

Conclusions: The histopathological diagnosis of bacterial lesions are of utmost importance as it is more reliable than culture in circumstances of reduced tissue availability. Early reporting is extremely necessary to reduce complications related to bacterial lesions.


Keywords


AFB, Bacteria, Culture, Special stains

Full Text:

PDF

References


McAdam AJ, Milner DA, Sharpe AH. Infectious diseases. In: Kumar V, Abbas AK, Aster JC, eds. Robbins and Cotran Pathologic Basis of Disease. 9th edn. Philadelphia, PA: Elsevier; 2015:341-402.

Ramakrishna BS. Helicobacter pylori infection in India: the case against eradication. Indian J Gastroenterol. 2006;25(1):25-8.

Garg B, Sandhu V, Sood N, Sood A, Malhotra V. Histopathological analysis of chronic gastritis and correlation of pathological features with each other and with endoscopic findings. Pol J Pathol. 2012;63(3):172-8.

World gastroenterology organization global guideline. Helicobacter pylori in developing countries. J Dig Dis. 2011;12(5):319-26.

Dandin AS, Pawale J, Athenian VS. H. pylori associated gastritis. J Clin Diagn Res. 2012;6(2):211-4.

Dogar TD, Khan SA, Jaffer R, Majid S, Qureshy A. Identification of Helicobacter pylori in gastric biopsies: a comparison of haematoxylin and eosin staining with immunohistochemistry. Biomedica. 2012;28(2):121-5.

Abu-Ahmad NM, Odeh A, Sallal AK. Prevalence of Helicobacter pylori gastritis at the North of Jordan. Jordan J Biol Sci. 2011;147(620):1-6.

Zaman K. Tuberculosis a global health problem. J Health Popul Nutr. 2010;28(2):111-3.

Kumar VS, Nookala L, Prakash S, Vivean PR. Ziehl-Neelsen (ZN) stained method: presence and absence of acid fast bacilli (AFB) of pulmonary and non-pulmonary tuberculosis patients under went anti-tuberculosis treatment. Res J Pharm Tech. 2015;8(5):529-32.

Jabe AS, Manhil K, Alfayyadh I, Hamim SS. Prevalence of tuberculosis from 2010-2015 in Nasiriyah City/Iraq. Res J Pharm Tech. 2019;12(5):2275-8.

Ridley DS, Jopling WH. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis. 1966;34(3):255-73.

Nandwani RR, Krishnan MG, Gupta U, Jain M. Clinical and cyto-histopathological study of Hansen’s disease in teaching government hospital in Mahakausal Region. Int J Med Res Rev. 2016;4(9):1713-21.

Bhargava D, Bhusnurmath B, Sundaram KR, Raman R, Al Okbi HM, Al Abri R, et al. Tonsillar actinomycosis: a clinicopathological study. Acta Tropica. 2001;80(2):163-8.

Aydin A, Erkiliç S, Bayazit YA, Koçer NE, Ozer E, Kanlikama M. Relation between actinomycosis and histopathological and clinical features of the palatine tonsils: a comparative study between adult and pediatric patients. Rev Laryngol Otol Rhinol. 2005;126:95-8.

Van Lierop AC, Prescott CA, Sinclair-Smith CC. An investigation of the significance of Actinomycosis in tonsil disease. Int J Pediatr Otorhinolaryngol. 2007;71:1883-8.

Toh ST, Yuen HW, Goh YH. Actinomyces colonization of tonsils: a comparative study between patients with and without recurrent tonsillitis. J Laryngol Otol. 2007;121:775-8.

Sujata N, Manimaran M, Rajeswara RN, Kafeel HA, Swayam JS. Histopathological features of tonsils and significance of actinomycosis in chronic tonsillitis. J Dent Med Sci. 2015;14:105-9.

Gaffney R, Harrison M, Walsh M, Sweeney E, Cafferkey M. The incidence and role of actinomyces in recurrent acute tonsillitis. Clin Otolaryngol Allied Sci.1993;18:268-71.