@article{Shah_Dongre_Karle_2021, title={Histomorphological spectrum of central nervous system lesions in a tertiary care hospital}, volume={10}, url={https://www.msjonline.org/index.php/ijrms/article/view/10430}, DOI={10.18203/2320-6012.ijrms20215036}, abstractNote={<p class="abstract"><strong>Background:</strong> Central nervous system (CNS) lesions show considerable geographic and racial variations with respect to the incidence and their pattern of distribution. CNS neoplasm account for 2% of all cancers. There has been a rapid increase in incidence of CNS tumors. Many non-neoplastic CNS lesions can clinically and radiologically mimic brain tumors and to differentiate them histopathological examination is necessary.</p><p class="abstract"><strong>Methods:</strong> This was a descriptive cross-sectional study of 30 cases, carried out from March 2020 to February 2021, in a tertiary health care hospital. The cases were diagnosed histopathologically and categorized according to the WHO 2021 classification.</p><p class="abstract"><strong>Results:</strong> The study included 30 cases. 3 (10%) of them were non-neoplastic while 27 (90%) were neoplastic with glioblastoma and diffuse astrocytoma being the most common. Overall, tumors of neuroepithelial tissue (60%) was the most common entity. Frontal lobe was the most commonly observed site in the neoplastic lesion. Headache was the most common presentation. Age range varied from 7 years to 66 years with the mean age of 32.7 years.</p><p class="abstract"><strong>Conclusions:</strong> The spectrum of neoplastic lesions were astrocytoma, glioblastoma, ependymoma, hemagioblastoma, medulloblastoma, meningioma, non-hodgkins lymphoma, oligodendroglioma, pitutary adenoma, schwannoma and non-neoplastic were A-V malformation, brain abscess, subdural empyema.</p>}, number={1}, journal={International Journal of Research in Medical Sciences}, author={Shah, Hetal Kirit and Dongre, Suryakant and Karle, Ravindra}, year={2021}, month={Dec.}, pages={86–91} }